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Rat Chrm4 Stable Cell Line-CHO
Category:Health & Medical/Drugs/Other Drugs
  • Post Date:2019-02-27 23:27:56
  • Expiry Date:1 year
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  • Payment Method:T/T,L/C
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Muscarinic acetylcholine receptors are relatively abundant and mediate many of the diverse actions of acetylcholine in the CNS, as well as throughout non-nervous tissues innervated by the parasympathetic nervous system. There are five muscarinic receptor subtypes referred to as M1, M2, M3, M4 and M5 which belong to GPCR superfamily. The odd-numbered muscarinic receptors (M1, M3, M5) couple efficiently through Gq/11, to activate of phospholipase C, that initiates the phosphatidylinositol turnover response. The even-numbered muscarinic receptors (M2, M4) inhibit adenylyl caclase activity via activation of the Gi class of G proteins. M2 and M4 receptors also activate G protein-coupled potassium channel, which leads to hyperpolarization of the plasma membrane of excitable cells. https://www.creative-biogene.com/Rat-Chrm4-Stable-Cell-Line-CHO-196457-12.html
Creative Biogene provides kits, reagents, and services that help researchers explore questions about gene discovery, regulation, and function. Creative Biogene holds a leadership position in the global market and is committed to improving the human condition through biotechnology. Creative Biogene is a US-based manufacturer and provider of genomics and proteomics products and services for academic and governmental research institutes, pharmaceutical and biotechnology industry.
Muscarinic acetylcholine receptors are relatively abundant and mediate many of the diverse actions of acetylcholine in the CNS, as well as throughout non-nervous tissues innervated by the parasympathetic nervous system. There are five muscarinic receptor subtypes referred to as M1, M2, M3, M4 and M5 which belong to GPCR superfamily. The odd-numbered muscarinic receptors (M1, M3, M5) couple efficiently through Gq/11, to activate of phospholipase C, that initiates the phosphatidylinositol turnover response. The even-numbered muscarinic receptors (M2, M4) inhibit adenylyl caclase activity via activation of the Gi class of G proteins. M2 and M4 receptors also activate G protein-coupled potassium channel, which leads to hyperpolarization of the plasma membrane of excitable cells. https://www.creative-biogene.com/Rat-Chrm4-Stable-Cell-Line-CHO-196457-12.html
010-631-6197922
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Creative Biogene
[United States]
Contact:Mr Wendy Wilson
Address:
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel:010-631-6197922
Fax:010-631-6147828
Http:www.creative-biogene.com
E-mail:contact@creative-biogene.com