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Human KCNH2 Stable Cell Line-HEK293
Category:Health & Medical/Drugs/Other Drugs
  • Post Date:2019-02-27 23:23:07
  • Expiry Date:1 year
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The human KCNH2 gene encodes the pore-forming subunit of Kv11.1, the voltage-gated hERG potassium channel. HERG channels are upregulated in some types of cancer and may serve as a tumor marker. KCNH2 mutations cause inherited forms of cardiac disorders including both long QT (loss-of-function) and short QT (gain-of-function) syndromes. Inhibition of HERG channels by pharmaceuticals is the primary cause of acquired long QT syndrome and drug-induced torsade de pointe. Therefore, HERG is an anti-target in cardiac risk assessment. https://www.creative-biogene.com/Human-KCNH2-Stable-Cell-Line-HEK293-196441-12.html
Creative Biogene provides kits, reagents, and services that help researchers explore questions about gene discovery, regulation, and function. Creative Biogene holds a leadership position in the global market and is committed to improving the human condition through biotechnology. Creative Biogene is a US-based manufacturer and provider of genomics and proteomics products and services for academic and governmental research institutes, pharmaceutical and biotechnology industry.
The human KCNH2 gene encodes the pore-forming subunit of Kv11.1, the voltage-gated hERG potassium channel. HERG channels are upregulated in some types of cancer and may serve as a tumor marker. KCNH2 mutations cause inherited forms of cardiac disorders including both long QT (loss-of-function) and short QT (gain-of-function) syndromes. Inhibition of HERG channels by pharmaceuticals is the primary cause of acquired long QT syndrome and drug-induced torsade de pointe. Therefore, HERG is an anti-target in cardiac risk assessment. https://www.creative-biogene.com/Human-KCNH2-Stable-Cell-Line-HEK293-196441-12.html
010-631-6197922
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Creative Biogene
[United States]
Contact:Mr Wendy Wilson
Address:
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel:010-631-6197922
Fax:010-631-6147828
Http:www.creative-biogene.com
E-mail:contact@creative-biogene.com