Naringenin

Naringenin Product Name Naringenin Latin Name Naringenin Molecular Formula C15H12O5 Molecular Weight 272.25 CAS NO 93602-28-9 Appearance White-like powder Product Content ≥98% Analytical Method HPLC Product Origin Citrus paradisi Macfadyen Action and Uses Naringenin is a potent inhibitor of the cytochrome p450 liver enzymes: CYP1A2, CYP3A3 and CYP3A4. There is however, considerable inter-individual variability in the effects of grapefruit juice on drug metabolism, in part due to 1) amount of naringenin formed by an individual, 2) amount of naringin present in a brand of grapefruit juice, 3) dilution of grapefruit juice used, and 4) other substances in grapefruit juice accounting for the interaction.2 Researchers at the University of Western Ontario in London discovered, while using various juices to hide the taste of a test substance given to patients along with their drugs as part of a cancer trial, that there was a synergistic or more effective action of the drug to breast cancer when it was given with Grapefruit Juice. From here, researchers launched studies of other fruits to find out why, and this is what they discovered. Human breast cancer cells in test tubes that were estrogen-insensitive; that is, the cells did not need estrogen to cock and prime them into maligency, respond well to a flavonoid found in grape juice, naringenin. Naringenin proved almost 8 times more potent at halting breast cancer cells's growth than another flavonoid, genestein from soy beans. You can now get the extract of the grape in capsule form. Ask for Resveratrol at your favorite health food store. Analysis Product content Naringenin≥98% Sieve analysis 100% pass 80 mesh Loss on Drying ≤5.0% Residue on Ignition ≤1.0% Heavy Metal <20ppm As <2ppm Residual Solvents <0.3% Microbiology Total Plate Count <1000cfu/g Yeast & Mold <100cfu/g E.Coli Negative Salmonella Negative Conclusion Conform with specification Storage Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation Shelf life 2 year when properly stored