4-Dimethylaminopyridine
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Usage:
Catalytic acylation reaction: It is a super-strong nucleophilic acylation catalyst that can significantly catalyze the acylation of highly sterically hindered and low-reactivity alcohols and amines. Its activity is approximately \(10^4\) - \(10^6\) times that of pyridine. It can be used in the production of active pharmaceutical ingredients such as acetyl(propionyl)spiramycin, artemisinin succinate, and statin lipid-lowering drugs.
Other reactions: It can also be used to catalyze silylation reactions of alcohols, lactonization reactions, etc., and can be used as a phase transfer catalyst for interfacial reactions. In pesticide production, it has obvious catalytic activity for the synthesis of allethrin and the synthesis of carbamates from isocyanates.
CAS NO: 1122-58-3
EC NO: 214-353-5
Molecular Formula: C7H10N2
Molecular Weight: 122.1698
Aliases: ;4-(Dimethylamino)pyridine;γ-(Dimethylamino)pyridine;N,N-Dimethyl-4-pyridinamine;Dimethylaminopyridine;4-Dimethylaminopyridine;4-Dimethylaminopyridine;DMAP;P-Dimethylaminopyridine;4-Dimethylaminopyridine;4-(Dimethylamino)pyridine;N,N-Dimethylaminopyridine;4-(Dimethylamino)pyridine;p-Dimethylaminopyridine;4-Dimethylaminopyridine;DMAP(4-Dimethylaminopyridine);
| Industry Category: | Chemicals/Heterocyclic Compounds/Pyridine |
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