1-Dodecanethiol

Main Applications

The core function of n-Dodecanethiol is closely related to the hydrophobicity of its long-chain alkyl group and the reactivity of its thiol group. It is primarily applied in the following fields:

Polymer Synthesis Industry

As a chain transfer agent: In free-radical polymerization reactions (such as the polymerization of monomers like styrene, acrylonitrile, and vinyl chloride), it controls the molecular weight of the polymer through the chain transfer action of the thiol group, regulates product viscosity and molecular weight distribution, and makes the polymer molecular weight more uniform. For example, in the synthesis of styrene-butadiene rubber (SBR), adding n-Dodecanethiol can reduce the molecular weight of the rubber and improve its processing performance.

Metal Surface Treatment

Used as a metal corrosion inhibitor: The thiol group can adsorb onto the surface of metals (such as copper and silver), forming a protective layer that prevents the metal from corroding or oxidizing. It is commonly used in metalworking fluids and rust inhibitors.

Preparation of Self-Assembled Monolayers (SAMs): On the surfaces of precious metals like gold and silver, dodecanethiol spontaneously assembles into an ordered monolayer via Au-S bonds, used for modifying electrodes, sensor surfaces, or preparing superhydrophobic materials.

Pharmaceuticals and Fine Chemicals

As an organic synthesis intermediate: Used to synthesize sulfide compounds, drug molecules, or pesticide intermediates. For example, the long-chain alkyl group is introduced via the reaction of the thiol group to adjust the lipophilicity of the target molecule.

Other Fields

Lubricant additives: Improve the extreme pressure performance and oxidation resistance of lubricants.

Cosmetic raw materials: Used in small amounts as conditioning agents, utilizing its hydrophobicity to improve the skin feel or stability of the product (odor needs to be controlled).