4-Dimethylaminopyridine
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- Email:shanyuan@shbrchem.com sales@baoruichem.com
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Usage:
Catalyzing acylation reactions: It is a super-strong nucleophilic acylation catalyst that can significantly catalyze the acylation reactions of highly sterically hindered and low-reactivity alcohols and amines. Its activity is approximately \(10^4\) - \(10^6\) times that of pyridine. It can be used in the production of active pharmaceutical ingredients such as acetyl(propionyl)spiramycin, artemisinin succinate, and statin lipid-lowering drugs.
Other reactions: It can also be used to catalyze silylation reactions of alcohols, lactonization reactions, etc., and can serve as a phase-transfer catalyst for interfacial reactions. In pesticide production, it exhibits significant catalytic activity for the synthesis of allethrin, the synthesis of carbamates from isocyanates, and other reactions.
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