1-O-Acetyl-2,3,5-tri-O-benzoyl-β-D-ribose

Chemical name: 1-O-Acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose

English name: 1-O-Acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose

Molecular formula: C₂₈H₂₄O₉

Molecular weight: 504.48

CAS No.: 6974-32-9

EC No.: 230-220-4

Molecular structure:

Quality standard:

Appearance: White to off-white crystals. Insoluble in water, soluble in alcohol.

Usage: This product is an important pharmaceutical raw material and intermediate. It is used in the synthesis of antitumor drugs such as azacitidine and selenazofurin, nucleoside antibiotics like toyocamycin and its analogs, and vasodilator/hypotensive/anticoagulant drugs such as 2-chloro-N6-methyladenosine. It is also used to synthesize: ① Antitumor-active adenosine, uridine, guanosine, cytidine, and purine nucleoside analogs, such as thiazole/pyrazole/pyridine/pyrrole/imidazole-fused pyrimidinone nucleosides, thiazole carboxamide nucleosides, phosphazole[4,5-d]pyrimidine nucleosides, halo-imidazole[4,5-c]pyridine(one) nucleosides, 2-/or 7-chloro(fluoro)-9-deazaadenosine, clitocine, and antileukemic 2-fluoro-/or 7-methyl-9-deazaadenosine; ② Various antiviral and antibacterial agents, such as 5-butylpyrimidine nucleoside against poliomyelitis and IHD strain vaccinia virus, benzylthiopurine nucleoside against Toxoplasma gondii virus, N3,5’-cyclic-4-ribosyl-linked-triazole[4,5-b]pyrimidin-5-one and analogs against flaviviruses especially hepatitis C virus, thieno[2,3-d]pyrimidine nucleoside against Escherichia coli, isatin nucleoside against herpes simplex virus, N-ribosyl 2-/and 8-halo-4H-1,4-benzothiazine with anti-Bacillus subtilis and anthelmintic activity, phenothiazine nucleoside with anti-Candida albicans, coagulase-negative staphylococci and antioxidant activity, 3-fluoro-10H-phenothiazine nucleoside with anti-Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, Bacillus cereus and antioxidant activity, thieno[2,3-d]pyrimidine thionucleoside against Escherichia coli, Bacillus subtilis, Candida albicans, and Aspergillus niger, pyrido[2,3-d]pyrimidine nucleoside against Escherichia coli, Staphylococcus aureus, Aspergillus niger, and Aspergillus flavus, ribosyl triazinone (thione) against Aspergillus fumigatus, Penicillium, Syncephalastrum racemosum, Candida albicans, Escherichia coli, 6-benzylamino-2-thio-pyrimidinone nucleoside against Escherichia coli, Staphylococcus aureus, Candida albicans; ③ Adenosine deaminase inhibitor triazole[3,4f]triazine-C-nucleoside, TOLL-like receptor agonist pyrido[2,3-d]pyrimidinone nucleoside, queuosine (a rare nucleoside found in T-RNA), pterin ribonucleoside, deoxyribose and its derivatives, etc.

Packaging: 10kg/drum or as per customer requirements.

Shelf life: 2 years