β-D-Galactose pentaacetate

Chemical name: 1,2,3,4,6-β-D-Galactose pentaacetate; β-D-Pentaacetylgalactose; β-D-Pentaacetyl galactose; 1,2,3,4,6-Penta-O-acetyl-β-D-galactopyranose;

English name: β-D-Galactose pentaacetate; Pentaacetyl-β-D-galactopyranose; Pentaacetyl β-D-galactose; 1,2,3,4,6-Penta-O-acetyl-β-D-galactopyranose

Molecular formula: C₁₆H₂₂O₁₁

Molecular weight: 390.34

CAS No.: 4163-60-4

EC No.: 224-008-0

Molecular structure formula:

Quality standard:

Properties: This product is a white crystalline powder, insoluble in water, easily soluble in organic solvents such as ethanol and chloroform.

Uses: Mainly used in biochemical reactions and pharmaceutical intermediates, specifically as follows:

1. Can be used to synthesize 3-ethoxycarbonylphenyl-β-D-acetyl galactoside for the treatment of depression.

2. Used to synthesize 1,2-trans-glycoside derivatives of oxazole compounds, which can serve as antitumor drugs, inhibiting microtubule assembly and selectively targeting tumor blood vessels.

3. Used to synthesize sugar ester derivatives of artemisone acid, which are synthesized from artemisone acid and fully acetylated brominated sugar as raw materials. Experimental results show that compounds 2d and 2g have good inhibitory effects on influenza A (H3N2) virus, and byproduct 3 has good inhibitory effects on both influenza A (H3N2, H1N1) and influenza B viruses.

4. Synthesis of β‑D‑galactosamine pentaacetate as a pharmaceutical intermediate.

5. Synthesis of β‑galactose-modified nitric oxide slow-release hydrogel for the treatment of periodontitis.

6. Synthesis of novel trimethyl citrate-d-galactoside, which has inhibitory effects on the central nervous system.

7. Used to prepare zein and glycopeptide graft copolymers, and corresponding electrospun fiber membranes are prepared by electrostatic spinning technology for use as hepatocyte scaffold materials.

8. F-labeled elemental galactose derivatives are used as tomography probes, which can serve as alternative glucose metabolic imaging agents for clinical examination and quantification.

9. Synthesis of novel sulfated sugar polymers, which can be used to treat and/or regulate inflammation, or to treat and/or prevent ischemia, including the treatment and/or prevention of ischemia-reperfusion injury or ischemic stroke, cancer treatment, and organ transplantation.

10. Used to synthesize tenofovir derivatives with antiviral efficacy, which can accumulate in the liver and slowly release active ingredients, offering high efficacy and low toxicity.

11. Used as a recyclable binder for metal casting molds and injection molding of metal and ceramic parts.

12. Can be used as a material for the proximal cap of vascular closure plugs.

13. Synthesis of isopropyl‑β‑D‑thiogalactoside (IPTG), a highly potent inducer. Alternatively, synthesis of the more stable thiogalactoside IBCG for inducing gene expression to produce recombinant proteins as functional substitutes for IPTG.

14. Used to prepare 4-methylumbelliferyl-β-D-galactopyranoside, an important fluorescent substrate commonly used to detect coliform bacteria in water and food. As a glycosidase substrate, it can be used for the analysis of corresponding glycosidase activity and for microbiological detection and human disease diagnosis where specific glycosidases are important indicators.

15. Preparation of β-galactosidase chromogenic substrates using 4-nitro-1-naphthol or its derivatives as chromophores.

16. Used to prepare fluorescent compounds, which are then used to make sensing films for sensitive detection of hydrogen chloride vapor.

17. Synthesis of 1‑thiophenyl‑2,3,4‑tri‑O‑benzyl‑6‑O‑substituted acyl‑1‑deoxy‑β‑D‑galactose ester as a galactose sugar ester donor.

18. Used for the preparation of novel oxime-linked polysaccharides and the synthesis of 6-azido-2,4-diacetamido-2,4,6-trideoxy-D-mannose.

19. Preparation of glycosylated nanofibers for protein recognition.

Storage: Store sealed in a cool, dry place.

Packaging: 25 kgs/drum or as per customer requirements.

Shelf life: 2 years.