5000L Injection Reagent Purified Water Equipment

# 5000L Injection Reagent Purified Water Equipment Process 

 ## 1. Raw Water Pretreatment Raw water is the basis for preparing purified water for injection reagents, typically sourced from municipal water supplies or other sources that meet drinking water standards. The first step is sand filtration to remove large suspended particles such as sediment and rust, which protects subsequent equipment from physical wear and clogging. Next is activated carbon filtration, which effectively adsorbs organic matter, residual chlorine, and some heavy metal ions in the water. For water used in injection reagents, residual chlorine may react with drug components, and organic matter can serve as a nutrient source for microbial growth. Activated carbon filtration significantly reduces these risks. Then, softening treatment is performed using ion exchange resins to remove hardness ions such as calcium and magnesium from the water, preventing scale formation during subsequent heating or membrane treatment processes. Scale can affect the heat transfer efficiency of equipment and the performance of membranes, thereby impacting the quality of purified water. 

 ## 2. Reverse Osmosis Treatment The pretreated raw water enters the reverse osmosis system, which is a critical step. Under pressure, the reverse osmosis membrane allows only water molecules to pass through, while exhibiting a high rejection rate for dissolved salts, colloids, bacteria, viruses, and large organic molecules. For a treatment capacity of 5000L, multiple sets of reverse osmosis membrane modules are required to operate in parallel. During the reverse osmosis process, parameters such as inlet pressure, temperature, and recovery rate are strictly controlled to ensure stable and efficient operation. This step removes approximately 99% of ions, significantly reducing the water's conductivity and greatly enhancing its purity.

 ## 3. Ion Exchange Refinement After reverse osmosis, trace ions may still remain in the water. Ion exchange refinement is used to further remove these ions. A mixed-bed ion exchange resin is employed, where cation exchange resins and anion exchange resins are uniformly mixed in the same exchange bed. This allows for more thorough removal of residual ions in the water, further increasing the water's resistivity to meet the stringent requirements for extremely low ion content in purified water for injection reagents, ensuring the stability and safety of the injection reagents.

 ## 4. Ultrafiltration and Microfiltration Ultrafiltration uses ultrafiltration membranes to remove macromolecular substances, colloids, and pyrogens from the water. The pore size of ultrafiltration membranes allows small molecules and water to pass through while retaining large molecular impurities, which is crucial for preventing potential pyrogen reactions in injection reagents. Microfiltration serves as the final filtration step, using microfiltration membranes to remove residual tiny particles in the water, further enhancing the clarity and purity of the water. 

 ## 5. Disinfection and Storage The disinfection process can employ ozone disinfection or ultraviolet (UV) disinfection. Ozone disinfection utilizes the strong oxidizing properties of ozone to effectively kill microorganisms in the water, while UV disinfection achieves sterilization by damaging the DNA structure of microorganisms. The disinfected purified water is stored in specialized storage tanks made of high-quality 316L stainless steel, featuring smooth inner surfaces, no sanitary dead corners, and excellent sealing performance to prevent contamination by external microorganisms and impurities. The entire system is equipped with comprehensive monitoring devices to monitor water quality parameters in real-time, ensuring that the produced 5000L of purified water meets the high standards required for injection reagent production.