Hydroxypropyl-β-cyclodextrin

Hydroxypropyl-gamma-cyclodextrin

Chinese Name: Hydroxypropyl-gamma-cyclodextrin.

Chinese Aliases: Hydroxypropyl-GAMMA-cyclodextrin; Hydroxypropyl-γ-cyclodextrin; HP-γ-CD.

English Name: Hydroxypropyl-gamma-cyclodextrin

CAS Number: 128446-34-4

Molecular Formula: C63H110O45

Molecular Weight: 1587.54

Appearance: White powder.

Purity: 98.0～102.0%

Quality Standard: Enterprise standard.

Average Degree of Substitution: 4.0～5.6

Features and Applications: Raw material for chemical analysis reagents. Gamma-cyclodextrin consists of eight glucose units connected end-to-end to form a cyclic compound. Compared to beta-cyclodextrin, it has a larger cavity diameter (approximately 1.3 times that of beta-cyclodextrin), a larger cavity volume (about 1.6 times that of beta-cyclodextrin), better water solubility (12.5 times that of beta-cyclodextrin), and better cavity compatibility (no cyclic hydrogen bonds, non-rigid ring), making gamma-cyclodextrin more promising for applications than beta-cyclodextrin.
The water solubility of gamma-cyclodextrin is 23.2g/100ml (25°C), but in some cases, solubility still limits its application. After hydroxypropylation, the product hydroxypropyl-gamma-cyclodextrin has its water solubility further increased to 80g/100ml (25°C). Additionally, hydroxypropylated gamma-cyclodextrin is no longer a single pure compound but a mixture of various substitutions, making it less prone to forming crystalline inclusion compounds with guest molecules. Overall, hydroxypropyl-gamma-cyclodextrin exhibits higher water solubility and stronger resistance to crystallization.
Recommended for use in higher value-added products, such as pharmaceuticals, health products, cosmetics, and other specialty materials, or for the treatment of larger molecules that hydroxypropyl-beta-cyclodextrin cannot encapsulate.
Packaging Specifications: 50g, 500g, 10kg

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