1-(4-Nitrobenzoyl)-2,3,5-tri-O-benzyl-D-arabinofuranoside (ARA sugar)

Product Name: 1-(4-Nitrobenzoyl)-2,3,5-tri-O-benzyl-D-arabinofuranose (ARA Sugar)

English Name: 2,3,5-tri-O-benzyl-1-O-(4-nitrobenzoyl)-D-arabinofuranose

CAS: 52522-49-3

Alias: 1-(4-Nitrobenzoyl)-2,3,5-tri-O-benzyl-D-arabinofuranoside

Molecular Formula: C₃₃H₃₁NO₈

Molecular Structure Diagram:

Molecular Weight: 569.61

Melting Point: 86-88 °C

Detailed Description: Intermediate for Fludarabine and Nelarabine

Fludarabine is highly effective against B-cell chronic lymphocytic leukemia (CLL), particularly in patients who have not responded to conventional treatment regimens. It is also used in preconditioning regimens for aplastic anemia;

Nelarabine is used for the treatment of patients with T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL) who have not responded to or have relapsed after at least two chemotherapy regimens.

Keywords: Fludarabine, Nelarabine Intermediate, Intermediate for Fludarabine or Nelarabine, Pharmaceutical Intermediate