tert-Butyl 2-bromoisobutyrate

tert-Butyl 2-bromoisobutyrate_23877-12-5_High Purity tert-Butyl 2-Bromoisobutyrate_Pharmaceutical Intermediate

Core Product Parameters:

tert-Butyl 2-bromoisobutyrate (tert-Butyl 2-bromo-2-methylpropionate), CAS Registry Number 23877-12-5, molecular formula C8H15BrO2, molecular weight 223.11. This product is a colorless to light yellow transparent liquid at room temperature and is an important tert-carbon halogenated carboxylic acid tert-butyl ester. Due to the simultaneous presence of tert-butyl ester group and tert-carbon bromine atom in its molecule, it exhibits unique steric hindrance effects and reactivity, making it widely used as a pharmaceutical intermediate and protecting reagent.

Specifications and Quality Control:

We provide high-purity tert-Butyl 2-bromoisobutyrate products, with a standard specification of ≥99% (GC). Through advanced distillation processes and strict quality control, the product features low moisture, low acid value, and low impurity content. Each batch of product undergoes gas chromatography (GC) analysis to ensure stable and reliable quality, meeting various needs from laboratory research to industrial production.

Main Application Areas:

tert-Butyl 2-bromoisobutyrate is an important fine chemical intermediate, with its main applications including:

Pharmaceutical Intermediate: Used in the synthesis of antibiotics, antitumor drugs, ceftazidime side chains, and other pharmaceutical intermediates.

Protecting Reagent: Serves as a protecting group for carboxyl protection and deprotection reactions.

Functional Materials: Used in the preparation of special polymer materials.

Organic Synthesis: Acts as an important building block for the construction of complex molecules.

Peptide Synthesis: Used for carboxyl protection in polypeptide synthesis.

Research Reagents: Widely used in chemical research at universities and research institutions.

Usage, Storage, and Safety Guidelines:

This product should be handled in a well-ventilated environment. It must be stored sealed, protected from light, and kept in a cool, dry place. Operators must wear protective gloves, goggles, and other personal protective equipment to avoid contact with skin and eyes. This product has certain irritant properties. Please carefully review the MSDS (Material Safety Data Sheet) before use for specific safety operation guidelines.

Packaging, Logistics, and Technical Services:

We offer various packaging specifications: 250kg/drum for industrial packaging, as well as 100ml and 500ml reagent-grade packaging, with customized packaging services available. Each batch of product comes with quality documents such as COA (Certificate of Analysis) and MSDS (Material Safety Data Sheet), and third-party test reports can be provided upon request. We have a professional technical team to provide product application and technical support.

Supplier Strength: Why Global Customers Choose Longsheng Chemical?

Focus and Experience: Since its establishment in 1991, Longsheng Chemical has been dedicated for over 30 years to the R&D, production, and global sales of fine chemical intermediates such as brominated and chlorinated alkanes, hydroxy esters, and aromatic hydrocarbons. As a key R&D and production base for organic bromine series products in China, our deep process knowledge is the strongest guarantee of our product quality.

Production Capacity and Strategic Layout: The company headquarters and core production base are located in Yancheng City, Jiangsu Province. To meet the growing global market demand and enhance supply chain resilience, we established a wholly-owned subsidiary in Hebi City, Henan Province, in 2024—Hebi Haige Longsheng New Materials Co., Ltd. This new modern production base covers 370 acres with a total investment of 1 billion CNY. Upon full completion and operation, the company's total annual production capacity will exceed 50,000 tons. This strategic layout significantly enhances our capacity assurance, delivery stability, and market responsiveness in the field of high-end intermediates, aiming to build a world-class fine chemical and new materials industrial platform with "intelligent manufacturing + green environmental protection."

International Standard Quality System: The company strictly implements and maintains the ISO 9001:2015 quality management system and ISO 14001:2015 environmental management system. It has passed the internationally recognized SEDEX (SMETA) social responsibility audit, and many of its products have completed formal registration under the EU REACH regulation, ensuring smooth access to the international market. Our quality control center is equipped with advanced testing instruments such as gas chromatographs (GC), automatic Karl Fischer moisture titrators (KF Titrator), and UV spectrophotometers (UV Spectrophotometer), establishing a comprehensive QA/QC system that ensures full-process quality traceability and strict control from raw material intake to production process control and finished product release.

Global Market Recognition and Cooperative Reputation: Longsheng Chemical's products and services have gained widespread trust from global customers. Our products are steadily exported to Europe, North America, Japan, South Korea, Taiwan (China), India, Southeast Asia, and other regions and countries. We have established long-term, stable strategic partnerships with many international large-scale pharmaceutical companies and multinational chemical groups. We deeply understand that every cooperation marks the beginning of responsibility.

Our Commitment:

Yancheng Longsheng Chemical Co., Ltd. not only sells products but is also committed to providing stable and reliable high-quality products, competitive prices, fast and efficient logistics responses, and professional and timely technical services. We look forward to becoming your trustworthy, long-term, and stable strategic partner in the field of fine chemical intermediates. Welcome to inquire and discuss cooperation.