N,N-Dimethylacetamide

I. Basic Product Information

• Chemical Name: N,N-Dimethylacetamide
• Molecular Formula: C₄H₉NO
• Appearance: Colorless transparent liquid with a faint ammonia-like odor.
• Physical Properties:

  Parameter	Value
  Boiling Point	164–166°C
  Density (25°C)	0.936–0.937 g/cm³
  Flash Point	70–77°C (open cup)
  Solubility	Miscible with water, alcohols, ethers, esters, and other organic solvents

II. Core Characteristics

1. Strong Polar Aprotic Solvent: High thermal stability (does not decompose at boiling point), chemically stable, capable of activating compound molecules.
2. Low Toxicity: Oral LD₅₀ in rats is 3.59 g/kg (low toxicity category).
3. High Solvency: Excellent dissolving performance for polyurethane, polyimide resins, acrylic fibers, etc.

III. Main Application Areas

1. Chemical and Material Synthesis

• Synthetic Fibers:
  • Solvent for polyacrylonitrile (acrylic) spinning, improving fiber strength (15–20% enhancement).
  • Solvent for polyurethane spinning, enhancing coating precision (thickness deviation ±2 μm).
• Polymer Materials: Solvent for synthesizing polyamide resins and polyimide films.
• Extraction and Separation: Extraction of styrene from C8 fractions, achieving 99.7% purity.

2. Pharmaceuticals and Pesticides

• Drug Synthesis: Used as a solvent for antibiotics (e.g., cephalosporins) and pesticide insecticides, improving optical purity to 98.5%.
• Excipient for Injections: Used as a solubilizer in pharmaceutical preparations (must meet pharmacopoeia standards).

3. Electronics and Industrial Catalysis

• Electronic Materials: Solvent for polyamide-imide coatings, used in 5G cable insulation layers (retains 92% dielectric strength after thermal shock).
• Catalyst: Accelerates reactions such as halogenation, cyanation, and alkylation, improving product yield.

4. Other Applications

• Coatings/Inks: Paint remover and colorant solvent.
• Industrial Cleaning: Metal degreasing and circuit board cleaning agent.

IV. Safety and Regulations

• Operational Protection: Avoid skin contact; ensure ventilation in the working environment; inhalation limit ≤13 mg/m³ (EU REACH regulation).
• Storage Requirements: Store sealed, away from light, and keep away from fire sources (flash point ≥70°C).
• Regulatory Notes: Not listed in the hazardous chemicals catalog but must be managed as a combustible liquid.

Note: Physical property data are compiled from laboratory tests and industry standards; application cases refer to large-scale production practices.