Isopropylmagnesium chloride

Isopropylmagnesium chloride

Isopropylmagnesium chloride

Molecular formula: C3H7ClMg

Molecular weight: 102.85 English name: Isopropylmagnesium chloride

CAS No.: 1068-55-9

Packaging/Storage: 1. 500ml glass bottles; 200L iron drums and steel cylinders. 2. This product should be isolated from air and moisture to the greatest extent during use, and it is best to use it up once opened. If color difference or trace precipitation is found in the product, it will not affect the product performance. 3. Store at room temperature.

Basic Information

Appearance: Gray to brown liquid

Density: 0.975g/ml (25℃)

Boiling point: 66℃ (refers to the solvent, not the solute)

Flash point: -20℃

Concentration: 1.5M, 2.0M (tetrahydrofuran solution)

Properties

Reacts violently with water: Extremely sensitive to air and moisture, will react violently with water and release highly flammable propane gas.

Flammable: In humid air, due to the intense exothermic reaction, highly flammable propane gas will be released.

Stability: It should be operated and stored under the protection of anhydrous and oxygen-free inert gases (such as nitrogen or argon). Avoid contact with oxidizers, acids, alcohols, etc. at room temperature.

Applications

1. Pharmaceutical industry: As a key synthetic building block, it participates in the industrial production of various drugs and their intermediates. For example, it is used to synthesize key intermediates of the anti-migraine drug lasmiditan, the antiviral drug remdesivir, and BTK inhibitors for the treatment of hematological cancers. In addition, it can also be used to synthesize alkaloid compounds such as nicotine.

2. Pesticides and other fine chemicals: It has important applications in the pesticide field, for example, it is used to synthesize key intermediates of the triazolothione fungicide prothioconazole. At the same time, it is also widely used in the synthesis of various complex fine chemical products.

3. Special organic synthesis: It can be used to prepare various fine chemical intermediates, such as pyridine-2-boronic acid, pyridyl monoselenide, aromatic and heteroaromatic sulfonamides, and 2,6-diiodobenzaldehyde derivatives, etc.

Packaging/Storage

1. 500ml glass bottles; 200L iron drums and steel cylinders.

2. This product should be isolated from air and moisture to the greatest extent during use, and it is best to use it up once opened. If color difference or trace precipitation is found in the product, it will not affect the product performance.

3. Store at room temperature.