Crizotinib

Introduction Product Name Crizotinib CAS No. 877399-52-5 Synonyms PF-02341066; PF 2341066; 3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]pyridin-2-amine Molecular Formula C21H22Cl2FN5O Molecular Weight 450.34 MDL MFCD12407409 InChI 1/C21H22Cl2FN5O/c1-12(19-16(22)2-3-17(24)20(19)23)30-18-8-13(9-27-21(18)25)14-10-28-29(11-14)15-4-6-26-7-5-15/h2-3,8-12,15,26H,4-7H2,1H3,(H2,25,27)/t12-/m1/s1 Appearance White solid Property* Purity 99 % Melting Point 202-204 °C Boiling Point (760 mmHg) 599.2 °C Density 1.48 g/cm3 Refractive Index n 20/D 1.67 *The values provided are general information and not part of the product specification. Safety Data WGK Germany 3 Application Main Applications Crizotinib is an orally bioavailable agent belonging to the class of c-met/hepatocyte growth factor receptor (HGFR) tyrosine kinase inhibitors with potential antineoplastic activity. Packaging and Handling Grade Pharma Grade Packaging According to customer's request Storage and Transportation Storage in original sealed container. Recommended storage temperature: -20 °C. Protect from moisture, heat and foreign material.
Crizotinib is an orally bioavailable agent belonging to the class of c-met/hepatocyte growth factor receptor (HGFR) tyrosine kinase inhibitors with potential antineoplastic activity.

CAS NO:877399-52-5

EC NO:

Molecular Formula:C₂₁H₂₂Cl₂FN₅O

Molecular Weight:450.3367

Synonyms:;(5-(pyridin-3-yl)-1,3,4-oxadiazol-2-yl)methanamine;3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]pyridin-2-amine;3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-Pyridinamine;Crizotinib;PF2341066;2-pyridinamine, 3-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1h-pyrazol-4-yl]-;PF-02341066;

Molecular Structure: