Vandetanib

Introduction Product Name Vandetanib CAS No. 443913-73-3 (338992-00-0) Synonyms Zactima; ZD6474; AZD-6474; ZD-6474; 4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazoline; N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazolin-4-amine Molecular Formula C22H24BrFN4O2 Molecular Weight 475.35 MDL MFCD07772346 InChI 1/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27) Appearance White solid Property* Purity 99 % Melting Point 240-243 °C Boiling Point (760 mmHg) 538.2 °C Density 1.406 g/cm3 Flash Point 279.3 °C *The values provided are general information and not part of the product specification. Application Main Applications Vandetanib is an anti-cancer drug that is used for the treatment of certain tumors of the thyroid gland. It acts as a kinase inhibitor of a number of cell receptors, mainly the vascular endothelial growth factor receptor (VEGFR), the epidermal growth factor receptor (EGFR), and the RET-tyrosine kinase. Packaging and Handling Grade Pharma Grade Packaging According to customer's request Storage and Transportation Storage in original sealed container. Recommended storage temperature: -20 °C. Protect from moisture, heat and foreign material.
Vandetanib is an anti-cancer drug that is used for the treatment of certain tumors of the thyroid gland. It acts as a kinase inhibitor of a number of cell receptors, mainly the vascular endothelial growth factor receptor (VEGFR), the epidermal growth fact

CAS NO:443913-73-3;338992-00-0

EC NO:

Molecular Formula:C₂₂H₂₄BrFN₄O₂

Molecular Weight:475.35

Synonyms:;4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazoline;Vandetanib, Zactima, ZD6474;N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazolin-4-amine;AZD-6474;ZD-6474;N-(4-bromo-2-fluoro-phenyl)-6-methoxy-7-[(1-methyl-4-piperidyl)methoxy]quinazolin-4-amine;

Molecular Structure: