Zoledronic acid hydrate

Introduction Product Name Zoledronic acid hydrate CAS No. 165800-06-6 Synonyms Zoledronic acid monohydrate; NDC-zoledronate; Zoledronate; Zometa; Reclast ; Zoledronate; CGP42446A; ZOL 446; (1-Hydroxy-2-imidazol-1-yl-1-phosphono-ethyl)phosphonic acid hydrate; (1-hydroxy-2-imidazol-1-ylethylidene)diphosphonic acid monohydrate; PHOSPHONIC ACID, [1-HYDROXY-2-(1H-IMIDAZOL-1-YL)ETHYLIDENE]BIS-, MONOHYDRATE Molecular Formula C5H10N2O7P2.H2O Molecular Weight 290.1 MDL MFCD08448695 InChI 1/C5H10N2O7P2.H2O/c8-5(15(9,10)11,16(12,13)14)3-7-2-1-6-4-7;/h1-2,4,8H,3H2,(H2,9,10,11)(H2,12,13,14);1H2 Appearance Almost white powder Property* Purity 99 % Melting Point 238.9 °C Boiling Point (760 mmHg) 764 °C Flash Point 415.8 °C Refractive Index n 20/D 1.72 *The values provided are general information and not part of the product specification. Safety Data RIDADR UN 3077 WGK Germany 3 Hazard Class 9 Packing Group III Application Main Applications Zoledronic acid hydrate is a third-generation bisphosphonate that inhibits the prenylation of GTPases critical to the signaling events related to osteoclast-mediated bone resorption. Zoledronic acid hydrate has been used in the treatment of osteoporosis, Paget’s disease, metastatic bone disease, multiple myeloma, hypercalcemia of malignancy. Packaging and Handling Grade Pharma Grade Packaging According to customer's request Storage and Transportation Storage in original sealed container. Recommended storage temperature: -20 °C. Protect from moisture, heat and foreign material.
used in the treatment of osteoporosis

CAS NO:165800-06-6

EC NO:

Molecular Formula:C₅H₁₂N₂O₈P₂

Molecular Weight:290.1049

Synonyms:[1-HYDROXY-(1H-IMIDAZOL-1-YL)-PHOSPHONOETHYL] PHOSPHONIC ACID MONOHYDRATE;(1-hydroxy-2-imidazol-1-yl-1-phosphono-ethyl)phosphonic acid hydrate;(1-hydroxy-2-imidazol-1-ylethylidene)diphosphonic acid monohydrate;PHOSPHONIC ACID, [1-HYDROXY-2-(1H-IMIDAZOL-1-YL)ETHYLIDENE]BIS-, MONOHYDRATE;ZOLEDRONIC ACID MONOHYDRATE;ZoledronicacidforInjection;[1-hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl]bis(phosphonic acid) hydrate (1:1);

Molecular Structure: