Leptomycin A

Introduction Product Name Leptomycin A CAS No. 87081-36-5 Synonyms PD-118607; Antibiotic PD-118607; Antibiotic ATS-1287A; ATS 1287A, PD 118607, Jildamycin; 19-(3,6-Dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-6-hydroxy-3,5,7,9,11,15,17-heptamethyl-8-oxo-2,10,12,16,18-nonadecapentaenoic acid; 19-(3,6-Dihydro-3-methyl-6-oxo-2h-pyran-2-yl)-3,5,7,9,11,15,17-heptamethyl-6-hydroxy-8-oxo-2,10,12,16,18-nonadecapentaenoic acid Molecular Formula C32H46O6 Molecular Weight 526.70 MDL MFCD01711669 InChI 1/C32H46O6/c1-20(16-22(3)12-14-28-24(5)13-15-30(35)38-28)10-9-11-21(2)17-25(6)31(36)27(8)32(37)26(7)18-23(4)19-29(33)34/h9,11-17,19-20,24-28,32,37H,10,18H2,1-8H3,(H,33,34)/b11-9+,14-12+,21-17+,22-16+,23-19+ Appearance Yellow liquid Property* Purity 99 % Boiling Point (760 mmHg) 717.7 °C Density 1.079 g/cm3 Flash Point 224.2 °C Refractive Index n 20/D 1.544 *The values provided are general information and not part of the product specification. Safety Data RIDADR UN 1170 WGK Germany 1 Hazard Class 3 Packing Group II Application Main Applications Leptomycin A is an antifungal antibiotic that acts as an inhibitor of nuclear export by interacting with CRM1/exportin-1. Inhibits nucleo-cytoplasmic translocation of molecules such as the HIV-1 Rev protein and Rev-dependent export of mRNA. Packaging and Handling Grade Pharma Grade Packaging According to customer's request Storage and Transportation Storage in original sealed container. Recommended storage temperature: -20 °C. Protect from moisture, heat and foreign material.
an antifungal antibiotic

CAS NO:87081-36-5

EC NO:

Molecular Formula:C₃₂H₄₆O₆

Molecular Weight:526.704

Synonyms:;2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-3,5,7,9,11,15,17-heptamethyl-6-hydroxy-8-oxo;(2E,10E,12E,16Z,18E)-6-hydroxy-3,5,7,9,11,15,17-heptamethyl-19-(3-methyl-6-oxo-3,6-dihydro-2H-pyran-2-yl)-8-oxononadeca-2,10,12,16,18-pentaenoic acid;Leptomycin A;

Molecular Structure: