2-Chlorothiophene-5-carboxylic acid

Chinese Name

2-Chlorothiophene-5-carboxylic acid

Foreign Name

5-Chloro-2-thiophenecarboxylic acid

CAS

24065-33-6

Molecular Formula

C5H3ClO2S

Molecular Weight

162.59

Content

≥98%

Chinese Aliases

2-Chlorothiophene-5-carboxylic acid; 5-Chlorothiophene-2-carboxylic acid; 5-Chlorothiophene-2-formic acid; Rivaroxaban intermediate

Single Impurity

0.10%

Total Impurities

0.5%

Risk Phrases

R36/37/38

Safety Phrases

S26; S37/39

Appearance: Off-white solid powder

Density: 1.572 g/cm³

Melting Point: 146-150°C

Boiling Point: 287°C at 760 mmHg

Flash Point: 127.4°C

Vapor Pressure: 0.00119 mmHg at 25°C

Loss on Drying: 0.10%

Uses

An anti-inflammatory and antibacterial agent for poultry and livestock, primarily used to treat coccidiosis (cecal coccidiosis) in chickens, rabbits, and sheep, as well as chicken cholera and typhoid fever; it is an intermediate of the active pharmaceutical ingredient rivaroxaban, used for the prevention of venous thromboembolism (VTE) in adult patients undergoing elective hip or knee replacement surgery; rivaroxaban intermediate.