Negotiable

Category: Machinery & Equipment/Valves/Instrument Valves

Company: China Topper Forged Valve Manufacturer Co., Ltd.

Product Description: China Class 600 Forged Steel Globe Valve Manufacturer Offers Class 150 to Class 600 Forged Steel Globe Valve, Standard API 598, 2 Inch, Flanged End. Name: Forged Steel Globe Valve. Standard: API 598. Pressure: 150#, 300#, 600#. Size: 1/2" to 2".  End: Flanged. more>

Negotiable

Category: Chemicals/Chemical Intermediates/Intermediate Compounds

Company: MAXDRILL ROCK TOOLS CO.,LTD

Product Description: 7'', 4 Step 3 Wing 3 1/2'' API Reg Male Drag Bit Product Despcription Diameter Thread Weight Part No 70 API 2 3/8 Reg 1.3 09006-0000 76 API 2 3/8 Reg 1.4 09006-0010 80 API 2 3/8 Reg 1.5 09006-0030 86 API 2 3/8 Reg 1.6 09006-0040 89 API 2 3/8 Reg 1.8 09006-0020 100 API 2 3/8 Reg 2.3 09006-0050 114 API 2 3/8 Reg 2.4 09006-0070 120 API 2 3/8 Reg 3.8 09006-0080 127 API 2 3/8 Reg 3.9 09006-0090 139 API 2 3/8 Reg 4.4 09006-0100 150 API 3 1/2 Reg 4.8 09006-0140 152 API 2 3/8 Reg 4.9 09006-0150 152 API 3 1/2 Reg 5 09006-0160 165 API 3 1/2 Reg 8.1 09006-0170 172 API 3 1/2 Reg 8.4 09006-0190 180 API 3 1/2 Reg 8.6 09006-0180 200 API 2 3/8 Reg 8.7 09006-0191 200 API 3 1/2 Reg 8.9 09006-0210 215 API 3 1/2 Reg 9 09006-0211 225 API 3 1/2 Reg 9.5 09006-0220 250 API 3 1/2 Reg 10 09006-0230 250 API 2 3/8 Reg 10 09006-0221 300 API 3 1/2 Reg 13 09006-0225 350 API 3 1/2 Reg 15 09006-0230 more>

Negotiable

Category: Chemicals/Inorganic Salts/Other Inorganic Salts

Company: 武汉三江航天固德生物科技有限公司

Product Description: 1) Good solubility, with solubility greater than 7% at 20°C and greater than 20% at 50°C. 2) Suitable calcium content: 13.0%-14.0%. 3) High absorption rate: As a bio-fermented organic calcium, its absorption rate is higher than other calcium supplements, making it an ideal calcium fortifier. 4) Product specification: 98.0-103.0% 5) Quality standards: CP Chinese Pharmacopoeia, BP, USP, EP   more>

Negotiable

Category: Chemicals/Inorganic Salts/Other Inorganic Salts

Company: 武汉三江航天固德生物科技有限公司

Product Description: 1) Widely used in peritoneal dialysis solutions (CAPD) for kidney disease patients and renal dialysis fluids; 2) Sodium lactate is used as an electrolyte and dialysate in intravenous injections, as well as in intestinal disinfectants, mouthwash gargles, and bladder irrigation solutions; 3) Sodium lactate is also extensively used in the preparation of Ringer's solution, formulated into injections for the treatment of metabolic acidosis. 4) Product specification: ≥60% 5) Quality standards: CP Chinese Pharmacopoeia, BP, USP, EP more>

$750

Category: Others

Company: Hebei Crossing Drill Bit Manufacture Co Ltd

Product Description: 216mm TCI button bit,insert bit,thread 4 1/2" reg pin,iadc code 415,435, 417,437 515,525,535,545, 517,527,537,547 615,625,635,,617,627,637,737 512,522,532,612,622,632,732 ,Crossing drill bit MFG supplies                                                 PDC Bits Tri Cone Bits Split-Bits Spade Bits Chevron Bits Open, Sealed-Bearing, Dual Sealed Bearing types available                                                    Hebei Crossing Bit is one of the leading manufacturer for Quality PDC bits and Tricone bits in North of China ,we have exported drill bits to more than 30 countries . Crossing Drilling Tools maintains a great reputation in the well drilling,construction, HDD (horizontal directional drilling) ,exploration, water well, geothermal, mining, and oil & gas industries as a company that can provide dependability and high-quality products at excellent value.Our quality tools:Tricone bit ,PDC bit,Tricone Cutters(single rollers),PDC reamers,Drag bits ,HDD hole openers. Our custom-designed PDC bits are specifically designed and manufactured with directional drilling in mind. Our bits are extremely stable, durable and ‘directional’ friendly, which is of the utmost importance when trying to keep the bit in a thin wavering pay zone. It is this steerable bit technology, combined with high ROP, which gives Crossing an advantage in a highly competitive market. Our Mission: To guarantee each drill bit :Drills faster ,Lasts Longer216mm TCI button bit,insert bit,thread 4 1/2" reg pin,iadc code 415,435, 417,437 515,525,535,545, 517,527,537,547 615,625,635,,617,627,637,737 512,522,532,612,622,632,732 ,Crossing drill bit MFG supplies                                                 PDC Bits Tri Cone Bits Split-Bits Spade Bits Chevron Bits Open, Sealed-Bearing, Dual Sealed Bearing types available                                                    Hebei Crossing Bit is one of the leading manufacturer for Quality PDC bits and Tricone bits in North of China ,we have exported drill bits to more than 30 countries . Crossing Drilling Tools maintains a great reputation in the well drilling,construction, HDD (horizontal directional drilling) ,exploration, water well, geothermal, mining, and oil & gas industries as a company that can provide dependability and high-quality products at excellent value.Our quality tools:Tricone bit ,PDC bit,Tricone Cutters(single rollers),PDC reamers,Drag bits ,HDD hole openers. Our custom-designed PDC bits are specifically designed and manufactured with directional drilling in mind. Our bits are extremely stable, durable and ‘directional’ friendly, which is of the utmost importance when trying to keep the bit in a thin wavering pay zone. It is this steerable bit technology, combined with high ROP, which gives Crossing an advantage in a highly competitive market. Our Mission: To guarantee each drill bit :Drills faster ,Lasts Longer216mm TCI button bit,insert bit,thread 4 1/2" reg pin,iadc code 415,435, 417,437 515,525,535,545, 517,527,537,547 615,625,635,,617,627,637,737 512,522,532,612,622,632,732 ,Crossing drill bit MFG supplies                                                 PDC Bits Tri Cone Bits Split-Bits Spade Bits Chevron Bits Open, Sealed-Bearing, Dual Sealed Bearing types available                                                    Hebei Crossing Bit is one of the leading manufacturer for Quality PDC bits and Tricone bits in North of China ,we have exported drill bits to more than 30 countries . Crossing Drilling Tools maintains a great reputation in the well drilling,construction, HDD (horizontal directional drilling) ,exploration, water well, geothermal, mining, and oil & gas industries as a company that can provide dependability and high-quality products at excellent value.Our quality tools:Tricone bit ,PDC bit,Tricone Cutters(single rollers),PDC reamers,Drag bits ,HDD hole openers. Our custom-designed PDC bits are specifically designed and manufactured with directional drilling in mind. Our bits are extremely stable, durable and ‘directional’ friendly, which is of the utmost importance when trying to keep the bit in a thin wavering pay zone. It is this steerable bit technology, combined with high ROP, which gives Crossing an advantage in a highly competitive market. Our Mission: To guarantee each drill bit :Drills faster ,Lasts Longer216mm TCI button bit,insert bit,thread 4 1/2" reg pin,iadc code 415,435, 417,437 515,525,535,545, 517,527,537,547 615,625,635,,617,627,637,737 512,522,532,612,622,632,732 ,Crossing drill bit MFG supplies                                                 PDC Bits Tri Cone Bits Split-Bits Spade Bits Chevron Bits Open, Sealed-Bearing, Dual Sealed Bearing types available                                                    Hebei Crossing Bit is one of the leading manufacturer for Quality PDC bits and Tricone bits in North of China ,we have exported drill bits to more than 30 countries . Crossing Drilling Tools maintains a great reputation in the well drilling,construction, HDD (horizontal directional drilling) ,exploration, water well, geothermal, mining, and oil & gas industries as a company that can provide dependability and high-quality products at excellent value.Our quality tools:Tricone bit ,PDC bit,Tricone Cutters(single rollers),PDC reamers,Drag bits ,HDD hole openers. Our custom-designed PDC bits are specifically designed and manufactured with directional drilling in mind. Our bits are extremely stable, durable and ‘directional’ friendly, which is of the utmost importance when trying to keep the bit in a thin wavering pay zone. It is this steerable bit technology, combined with high ROP, which gives Crossing an advantage in a highly competitive market. Our Mission: To guarantee each drill bit :Drills faster ,Lasts Longer more>

Negotiable

Category: Others

Company: 江西全立森净化工程有限公司

Product Description: 原料药洁净厂房要求：非无菌原料药精制、干燥、粉碎、包装等生产操作的环境应当按照D级洁净区的要求设置。工艺布局要防止人流、物流之间的混杂和交叉污染，并符合下列要求。分别设置人员和物流进入生产区域的通道，必要时应设置极易造成污染的物料和废弃物的专用出入口；洁净区内的半成品不宜直接进入一般生产区，可采用传递窗（柜）、气闸或设置相应的设施进入一般生产区，传输带不得不同洁净级别区域。人员流动与净化的原则是使发生交叉污染的可能性最小；适当情况下采用气锁；一般应具备雨具存放﹑脱外衣换鞋﹑洗手消毒﹑穿洁净工衣﹑气闸等功能。洁净度按净化程序，由外及里逐次提高。气锁间两侧的门不应同时打开。可采用连锁系统，或光学或（和）声学的报警系统，或两侧相互可视，防止两侧的门同时打开；洁净厂房入口设双面净鞋设施(凳﹑台﹑柜)，供不同要求的鞋要能分开放置。洗手消毒间应设洗手盆﹑消毒和干手设施。进入洁净区域的原辅料﹑包装材料，应有清洁措施。可设置原辅料外包清洁室﹑包装材料清洁室﹑灭菌室等。洁净室或灭菌室之间应设置气闸室或传递窗(柜)；生产过程中废弃物出口不应与物料进口合用一个气闸或传递窗(柜)，宜单独设置废弃物传递装置。物料清洁室与洁净室（区）之间应设置气闸室或传递窗（柜），用于传递清洁或灭菌后的原辅料、包装材料和其他物品。传递窗（柜）两边的传递门，应有防止同时被打开的措施，密封性好并易于清洁。传递窗（柜）的尺寸和结构应满足传递物品的大小和重量所需要求。最终用于固体口服制剂的API 产品的操作区域（包括溶解、结晶、离心分离、干燥、混合、粉碎、包装等）其环境空气的洁净度必须符合无菌产品的D级区标准。对于最终原料将成为无菌产品的生产区域而言，其环境的洁净等级应达到无菌产品的C级标准。这通常要求为其提供高效过滤送风、低位回风、压力气锁室（将的粉体保持在洁净室内）、以及为验证房间洁净条件所需的仪表。而最终药品处理区的环境级别必须与这些API在其最终成品生产区的级别相一致。而对于最终生产无菌产品的API而言，其原料处理区的级别至少要满足C 级或 D级的要求，并配备有空气过滤、压差控制和气锁等。¡ 生产用洁净室应配有低位或高/低位组合式回风。¡ 在固体加料、料桶转运、人孔和液体溢出等部位需设置局部排风系统LEV。¡由于中间品的生产都处于密闭状态下，并且温度受到控制，因此环境区域不需要控制。¡ 一般而言，如没有易燃溶媒的存在，那么HVAC系统可以再循环。¡ AHU过滤应配备MERV 7和MERV 13。末端过滤器的等级评定应能适应产品要求。¡ 强效API排风不得回流到洁净室。建议为强效产品的排风采用洗气塔或HEPA过滤器。相关规范：《药品生产质量管理规范》2010GB 5045750687-2019医药工业洁净厂房设计标准GB 50073-2013 洁净厂房设计规范GB 51110-2015 洁净厂房施工及质量验收规范GB 50019-2015 工业建筑供暖通风与空气调节设计规范GB 50243-2016通风与空调工程施工质量验收规范GB 50016—2014（2018年版）建筑设计防火规范 more>

Negotiable

Category: Others

Company: 重庆佳和过滤技术有限公司

Product Description:      China is a major global producer of bulk drugs, with over1,500 bulk drug manufacturers nationwide. Simultaneously, China is also a leading exporter of bulk drugs globally, with exports exceeding10 million tons in2019. Data shows that China's production capacity for bulk drugs such as antibiotics and vitamins accounts for over60% of the global total, with more than50% exported, capturing1/5 of the global market share. Consequently, there are high demands for the production processes of bulk drugs, with production costs and product quality becoming key competitive factors for enterprises. The application advantages of membrane separation technology and equipment are increasingly prominent.     Membrane separation technology is characterized by high efficiency, energy savings, environmental friendliness, and high-precision separation. Proper use of membrane separation technology can replace traditional separation and filtration methods such as vacuum filtration, centrifugal separation, and plate and frame filtration, achieving better separation and filtration results. Ceramic membrane technology is a type of membrane separation technology, entirely made from high-purity inorganic metal oxides. It features a narrow pore size distribution, resistance to fouling, good chemical stability, high-temperature resistance, corrosion resistance, ease of sterilization, cleaning, and wear resistance.    Ceramic membrane technology and equipment can clarify and remove impurities from feed liquids such as bulk drug fermentation broths, extraction solutions, enzymatic hydrolysates, and mother liquors, achieving molecular-level separation of soluble impurities from target substances in the raw liquid. They also provide reliable room-temperature concentration and nanofiltration-level purification for bulk drugs. Compared to other hollow and spiral-wound membrane elements, ceramic membranes are more suitable for filtration processes.     Chongqing Jiahe Filtration Technology Co., Ltd. has long been committed to the development and application of solutions for filtration refinement, separation and purification, decolorization, and concentration in industries such as natural plant extraction, traditional Chinese medicine preparation, fermentation, and beverages.By widely applying membrane separation technology in industrial separation and purification, the company promotes circular and energy-saving production methods, helping users improve production efficiency and achieve clean production and energy conservation. It has independently completed numerous domestic and international ceramic nanofiltration concentration and separation projects, with extensive experience, a comprehensive customer service system, regular follow-ups, and guaranteed equipment quality. more>

$面谈

Category: Health & Medical/Medical Consumables/Other Medical Consumables

Company: 陕西圣瑞医药科技有限公司

Product Description: Pharmaceutical Grade Silver Sulfadiazine Burn Treatment API Powder 100g per BoxIn the field of burn treatment, pharmaceutical grade silver sulfadiazine has become a trusted medication for doctors and patients due to its unique efficacy. It is primarily used to prevent and treat infections secondary to second and third-degree burns, with particularly significant effects on second-degree burns. It is also effective in managing wound infections and skin mucosal infections caused by scalds or general trauma.Pharmaceutical grade silver sulfadiazine combines the dual actions of sulfadiazine and silver salts. It has a broad antibacterial spectrum, exhibiting strong antibacterial activity against most Gram-positive and Gram-negative bacteria. It effectively inhibits the growth and reproduction of bacteria at the wound site, creating a favorable environment for wound healing. Additionally, it has an astringent effect, promoting wound drying and scab formation, significantly shortening the healing time, and reducing patient discomfort.When using pharmaceutical grade silver sulfadiazine, it is typically applied topically. For small-area burns, the medication can be directly applied to the wound with a thickness of approximately 1 - 1.5mm, once daily. For larger burn areas, the ointment can be made into an oil gauze for application, also changed once daily. However, it is essential to strictly follow the doctor's guidance to ensure accurate dosage and application methods.It is worth noting that some patients may experience local irritation, rash, dermatitis, drug fever, or other allergic reactions after using pharmaceutical grade silver sulfadiazine. Since topical application may lead to partial absorption, systemic adverse reactions such as granulocytopenia, thrombocytopenia, aplastic anemia, impaired liver function, nausea, vomiting, and diarrhea may also occur. If these symptoms appear, the medication should be discontinued immediately, and the doctor should be informed for appropriate management.Overall, pharmaceutical grade silver sulfadiazine plays an irreplaceable role in burn treatment. However, proper usage and close attention to adverse reactions are key to ensuring its therapeutic effectiveness and patient safety.Pharmaceutical Grade Silver Sulfadiazine Burn Treatment API Powder 100g per BoxSilver sulfadiazine powder is commonly used to treat burn wounds and skin infections, offering antibacterial and anti-inflammatory effects. Due to its significant inhibitory effects on various bacteria and fungi, it plays a crucial role in clinical treatment. As a pharmaceutical ingredient, silver sulfadiazine powder must meet the stringent requirements of the Chinese Pharmacopoeia (CP edition) for purity, safety, and quality standards to ensure its safe, stable, and effective clinical use.Pharmaceutical Grade Silver Sulfadiazine Powder CP Edition Pharmacopoeia Quality Standards1. AppearanceSilver sulfadiazine powder that meets pharmacopoeia standards is a colorless to pale yellow crystalline powder. Its purity and color significantly impact the drug's efficacy and stability. The pharmacopoeia imposes strict requirements on the appearance and color of silver sulfadiazine powder to ensure product uniformity and applicability.2. IdentificationIdentification of silver sulfadiazine powder is primarily conducted through chemical reactions and ultraviolet-visible spectrophotometry. The pharmacopoeia specifies two identification tests:- Chemical identification: Confirms the presence of sulfonamide and silver ions through reactions with other reagents to ensure component accuracy.- Ultraviolet spectrophotometry: Silver sulfadiazine powder exhibits unique absorption peaks at specific wavelengths, meeting identification requirements.How effective is pharmaceutical grade silver sulfadiazine in treating small-area burns?How to use pharmaceutical grade silver sulfadiazine to prevent burn infections?Correct steps for treating scalds with pharmaceutical grade silver sulfadiazineHow effective is pharmaceutical grade silver sulfadiazine for second-degree burns?Successful cases of pharmaceutical grade silver sulfadiazine in treating skin wound infectionsApplication thickness requirements for pharmaceutical grade silver sulfadiazine ointmentSafety of pharmaceutical grade silver sulfadiazine in pediatric burn treatmentCommon adverse reactions and management methods for pharmaceutical grade silver sulfadiazineComparison of pharmaceutical grade silver sulfadiazine with commonly used burn medicationsPreventive measures for scars after burn treatment with pharmaceutical grade silver sulfadiazine more>

$面谈

Category: Chemicals/Inorganic Salts/Other Inorganic Salts

Company: 陕西圣瑞医药科技有限公司

Product Description: Pharmaceutical Grade Sodium Bicarbonate Baking Soda API Sample, 500g per Bag with QualificationSodium bicarbonate (NaHCO₃), commonly known as baking soda, is a common inorganic salt widely used in medical, food, cosmetic, and industrial fields. As a pharmaceutical-grade chemical, sodium bicarbonate is extensively applied in treating conditions such as hyperacidity, indigestion, and acidosis. It is also commonly used in respiratory therapy and as an adjunct treatment for kidney diseases. To ensure the safety and efficacy of sodium bicarbonate in medicinal applications, the "2020 Edition of the Chinese Pharmacopoeia" (CP Edition) has established strict quality standards for pharmaceutical-grade sodium bicarbonate, covering aspects such as appearance, content, impurities, and microbial limits.Pharmaceutical Grade Sodium Bicarbonate Baking Soda API Sample, 500g per Bag with QualificationMain Uses of Pharmaceutical Grade Sodium Bicarbonate:1. Relief Agent for HyperaciditySodium bicarbonate can be used to alleviate stomach discomfort caused by excessive gastric acid. It reacts with gastric acid to produce carbon dioxide and water, helping to neutralize acid in the stomach and relieve symptoms of heartburn and indigestion. Such medications are commonly found in oral tablets or oral solutions.2. Treatment of AcidosisAs an alkaline substance, sodium bicarbonate plays a significant role in the treatment of acidosis (such as metabolic acidosis). It alkalizes the blood to neutralize excess acid in the body, thereby restoring the acid-base balance of the blood.3. Respiratory ApplicationsIn the treatment of certain respiratory diseases (such as asthma and bronchitis), sodium bicarbonate helps alleviate the acidic environment in the airways, reducing patient discomfort.4. Adjunct Treatment for Kidney DiseasesIn patients with chronic kidney disease, sodium bicarbonate helps relieve metabolic acidosis caused by the accumulation of acidic substances and aids in maintaining the body's acid-base balance.5. Topical MedicationsSodium bicarbonate is also used in some topical medications, such as for local cleansing and relieving skin itching, particularly in skincare and cosmetic products.6. Food and Chemical IndustriesBeyond medical applications, sodium bicarbonate is widely used as a common leavening agent and cleaning agent in food processing and other chemical industries.Main products include:Common excipients for topical preparations: Glycerin/Propylene Glycol, Vaseline/Lanolin, Laurocapram, Stearic Acid, Triethanolamine, Poloxamer 188/407, Polysorbate 80, Polyethylene Glycol Series, Solid Paraffin, Liquid Paraffin (Light/Heavy), Mixed Fatty Acid Glycerides, and other varieties.Excipients for oral preparations: Honey/Sucrose, Lactose/Aspartame, Hydroxypropyl Beta-Cyclodextrin, Hypromellose, Methylcellulose, Ethylcellulose, Microcrystalline Cellulose, Povidone K30, Magnesium Stearate, Maltose/Saccharin Sodium/Sucralose/Tranexamic Acid/Stevioside, Gelatin, Pigment Lakes, Flavors, and other varieties.Excipients for injections: (Endotoxin & Microbial Limits Required)Cholesterol, Trehalose (Anhydrous/Dihydrate), Lecithin/Soybean Phospholipid, Polysorbate (for Injection), Citric Acid/Sodium Citrate, Sodium Dihydrogen Phosphate/Dipotassium Hydrogen Phosphate, Lactose (for Injection), Disodium Edetate (for Injection)Raw materials for topical disinfection and bacteriostasis:Chlorhexidine Acetate, Chlorhexidine Gluconate Solution, Benzalkonium Bromide/Benzalkonium Chloride, Menthol/Peppermint Oil, Salicylic Acid/Sodium Benzoate, Vitamin E Oil, Dimethicone, Span 80/85, Methylparaben/Ethylparaben/Propylparaben/Sodium Methylparaben/Sodium Propylparaben, Dibutyl Hydroxytoluene, Tromethamine, Chlorobutanol, Dihydroxyaluminum Aminoacetate, etc.Sterile Water for Injection, Silver Sulfadiazine, Vitamin A, Camphor, Borneol, Sodium Bicarbonate, Berberine, Pentoxyverine Citrate, Metformin, Artificial Cow Bezoar, Paracetamol, Simple Syrup, Dexamethasone, Glycerin, Potassium Citrate, Chitosan, Calamine, Roxithromycin, ProcaineAlso available for consultation: Food-grade products, extracts, reagents, intermediates, cosmetic raw materials, and export products. more>

Negotiable

Category: Machinery & Equipment/Valves/Gate Valves

Company: 自贡自泵球阀水泵有限公司

Product Description: Sichuan Zigong Valve High-Pressure Wellhead Valve API 6A Slab Gate ValveBefore inquiring or purchasing, users are requested to provide accurate parameters such as bore size, pressure, connection method, operation method, and main body material. The above prices are reference prices, and prices vary for different models. Additionally, this product is a customized product with a production cycle, and delivery times also vary. Therefore, for specific model prices and delivery times, please call for consultation.API 6A Slab Gate Valve The valve body and bonnet use metal-to-metal sealing, improving sealing performance. An inverted sealing mechanism is provided between the stem and bonnet to facilitate the replacement of stem sealing packing under pressure. The valve body is made of forged alloy steel with a no-through-hole design, eliminating external leakage. The sealing surface is hard-faced with hard alloy, providing corrosion resistance, erosion resistance, and wear resistance. The valve body gasket groove can be overlaid with austenitic stainless steel as per user requirements to enhance corrosion resistance and extend service life. Spring pre-loading is applied to the gate and seat, enabling bidirectional sealing. Equipped with open/close indicators to display valve status, with low operating torque.Pressure: 2000 Psi to 10000 PsiBore Size: 1-13/16" to 9" Operating Temperature: -20 to 120°CMedium: Water, Natural Gas, Oil, MudSlab Gate Valve Design Features:Non-rising stem design allows valve installation in space-limited areasSoft sealing design between the gate and seat ring (2000~5000 PSI)Dual seat ring design facilitates field maintenance (1000~15000 PSI)Full-bore structure design reduces turbulence and pressure dropRising stem design can be provided as per customer requirementsAPI 6A Slab Gate Valve Applications: Oilfields, Crude Oil/Natural Gas Extraction, Wellhead Equipment.Supplier: Zigong ZIPU Ball Valve Pump Co., Ltd. ZIPU VALVE & PUMP CO., LTD more>

$180

Category: Chemicals/Plastics & Products/Plastic Additives

Company: 湖北拓源精细化工有限公司

Product Description: Sodium Fructose Diphosphate API Injection Grade/Oral Grade 488-69-7 CAS Number Hubei Tuoyuan Direct Factory Sales with Quality Inspection ReportProduct Parameters【Chemical Name】D-Fructose-1,6-Diphosphate Trisodium Salt【English Name】D-Fructose-1,6-Diphosphate【CAS Number】488-69-7 | 【EINECS】207-683-6【Molecular Formula】C6H14O11P2 | 【Molecular Weight】324.1163【Properties】·White/off-white crystalline powder, slight characteristic odor, slightly salty taste·Easily soluble in water (highly hygroscopic), insoluble in ethanol·Complies with the standards of the Chinese Pharmacopoeia 2020 Edition【Indications】·Official Use: Hypophosphatemia caused by acute or chronic diseases (such as blood transfusion, parenteral nutrition, chronic alcoholism)·Pharmacological Action: Promotes ATP generation by activating phosphofructokinase, improving cellular energy metabolismPackaging and Transportation√Specification: 25kg/cardboard drum (laminated moisture-proof)√Grade:·Injection Grade: Complies with GMP standards·Oral Grade: Food-grade certified·Logistics: STO Express, YTO Express, ZTO Express, Yunda Express, Deppon/SF Express with cash on delivery (30% prepayment required for shipment, bulk purchases enjoy freight subsidies)Manufacturer Qualifications and Services【Hubei Tuoyuan Fine Chemicals】★ Key Enterprise in Hubei's Biomedical Industry (Unified Social Credit Code: 91420105MAEE9L781B)★Quality Commitment:·Strictly adheres to the quality standards of the Chinese Pharmacopoeia 2020 Edition·Full-process traceability, providing COA quality inspection report + MSDS manual★Service Guarantee:·12-hour response for technical inquiries·Quality issues: guaranteed return or replacement within 15 daysProcurement Guide①Applicable Customers:·Pharmaceutical intermediate manufacturers, hospital pharmacy departments, health product raw material purchasers②Minimum Order Quantity:·Laboratory Grade: Minimum order of 1kg (packaged in aluminum foil bags)·Bulk Purchase: Orders over 500kg enjoy price discounts③Payment Methods:·Corporate bank transfer (providing business license for account opening)Technical Documentation SupportValue-Added Services:oCustomized Chinese/English COA certificatesoCustomized packaging (requires 3-day advance reservation)☎Contact InformationOfficial Website: http://www.chemty.com24-Hour Hotline: 027-84700466     13260668040WeChat Customer Service: tuoyuanchem (Note "FDP Purchase" for priority approval)Address: Wantong Industrial Park, No. 336 Pengjialing, Hanyang District, Wuhan City, Hubei Province more>

$面谈

Category: Chemicals/Natural Extracts/Other Natural Extracts

Company: 陕西圣瑞医药科技有限公司

Product Description: Pharmaceutical Grade Berberine National Drug Standard Code API Medical Grade Berberine GMP Certified with QualificationsAccording to the "Chinese Pharmacopoeia 2020 Edition", the quality standards for pharmaceutical grade berberine mainly include the following:- Description: Yellow crystalline powder; odorless. Soluble in hot water, slightly soluble in water or ethanol.- Identification:- Take about 0.1g of the sample, add 10ml of water, heat gently to dissolve, then add 4 drops of sodium hydroxide test solution. After cooling, turbidity occurs.- Take about 5mg of the sample, stir, and it shows cherry red color.- The infrared absorption spectrum should be consistent with the reference spectrum (Spectrum Set 320).- Take about 0.1g of the sample, add 20ml of water, heat gently to dissolve, then add 0.5ml of nitric acid. Cool, let stand for 10 minutes, filter, and the filtrate shows the identification reaction for chlorides.- Tests:- Related substances: Determined by high-performance liquid chromatography. In the chromatogram of the test solution, if there are peaks with retention times consistent with jatrorrhizine and palmatine peaks, calculate by external standard method using peak area, neither should exceed 1.0%; the sum of other impurity peak areas should not be greater than the peak area of berberine in the reference solution (2.0%).- Synthetic products must be tested according to regulations and should comply.- Organic nitriles: For synthetic products, test by thin-layer chromatography. The test solution should not show impurity spots at the positions corresponding to the main spots of the reference solution.- Water: Water content should not exceed 12.0%.- Residue on ignition: Residue should not exceed 0.2% (extracted product) or 0.1% (synthetic product).- Heavy metals: Synthetic products should contain heavy metals not more than 20 ppm.- Assay: Calculated on the anhydrous basis, the content of C₂₀H₁₈ClNO₄ should be not less than 97.0% for extracted products and not less than 98.0% for synthetic products.Pharmaceutical Grade Berberine National Drug Standard Code API Medical Grade Berberine GMP Certified with QualificationsThe medical uses of berberine are mainly as follows:- Treatment of intestinal infections: Mainly used for treating gastroenteritis, bacterial dysentery, and other intestinal infections caused by sensitive pathogens such as Shigella and Vibrio cholerae. Its mechanism of action involves inhibiting various Gram-positive and Gram-negative bacteria, with the strongest antibacterial effect against Shigella.- Other effects: Berberine also has some inhibitory effects on hemolytic streptococci, Staphylococcus aureus, Neisseria meningitidis, Salmonella typhi, Corynebacterium diphtheriae, etc. It also shows some inhibitory effects on influenza viruses, amoebae, leptospira, and certain skin fungi, so it has been used clinically as an adjunct treatment for related diseases. Additionally, some studies have found that it has antiarrhythmic effects, but it has not been widely used in clinical practice. more>

Negotiable

Category: Machinery & Equipment/Valves/Gate Valves

Company: 自贡自泵球阀水泵有限公司

Product Description: Zigong Valve Z41F or Z43F Carbon Steel or Stainless Steel Soft Seal American Standard API6D Flat Gate ValveBefore inquiring or purchasing, users are requested to provide accurate parameters such as diameter, pressure, connection method, operation method, and main material. The above prices are reference prices, and prices vary for different models. Additionally, this product is custom-made with a production cycle, and delivery times also vary. Therefore, for specific model prices and delivery times, please call for consultation.API6D The flat gate valve is a sliding valve with a closure element in the form of a parallel gate. The closure element can be a single gate or a double gate with a spreading mechanism between them. The pressing force of the gate against the valve seat is controlled by the medium pressure acting on the floating gate or floating valve seat. In the case of a double gate flat gate valve, the spreading mechanism between the two gates can supplement this pressing force.API6D Flat gate valves can be divided into manual flat gate valves, pneumatic flat gate valves, and electric flat gate valves based on the driving method. According to their use and application, they can be categorized into flat gate valves with diversion holes, flat gate valves without diversion holes, oil field flat gate valves, pipeline flat gate valves, and gas flat gate valves, among others.API6D Flat gate valves are suitable for natural gas, petroleum, chemical, environmental protection, urban pipelines, gas pipelines, and other transmission pipelines, venting systems, and gas storage devices, serving as opening and closing equipment. Z43 type single gate flat gate valves with diversion holes are suitable for long-distance pipelines in natural gas extraction and purification.API6D Flat gate valve diameter range : DN25~1200 Pressure range: 0.6MPa~45MPa 150Lb~3000Lb Flat gate valves with diversion holes are used in pipelines that require pigging for cleaning, while those without diversion holes are used in pipelines that do not require pigging.API6D Flat gate valve advantages: Low flow resistance, with non-reduced ports having flow resistance similar to that of short pipes. Flat gate valves with diversion holes installed in pipelines can also be directly cleaned using pigs. Since the gate slides on two valve seat surfaces, flat gate valves are also suitable for media with suspended particles. The sealing surface of the flat gate valve is actually self-aligning. The valve seat sealing surface is not damaged by thermal deformation of the valve body. Moreover, even if the valve is closed in a cold state, thermal elongation of the valve stem will not overload the sealing surface.Supplier: Zigong ZIPU Ball Valve Pump Co., Ltd. ZIPO VALVE & PUMP CO., LTD more>

$面谈

Category: Chemicals/Pharmaceutical Raw Materials/Cardiovascular APIs

Company: 陕西圣瑞医药科技有限公司

Product Description: Pharmaceutical Grade Chlorhexidine Acetate (Chlorhexidine Acetate) Disinfectant and Antiseptic Bulk Drug CP Edition Pharmacopoeia StandardChlorhexidine Acetate is an antibacterial agent commonly used in the medical industry, widely applied in areas such as skin disinfection, oral care, and wound cleaning. As a potent antibacterial disinfectant, chlorhexidine acetate holds extensive application value in hospitals, clinics, and home care, particularly demonstrating significant effectiveness in preventing and treating skin infections and oral inflammations. In pharmaceutical-grade applications, the quality control of chlorhexidine acetate is especially important. The "2020 Edition of the Chinese Pharmacopoeia" (CP Edition) provides detailed regulations on the quality standards of chlorhexidine acetate to ensure its safety and efficacy in medical applications.Uses of Chlorhexidine Acetate:- Pharmaceutical Grade Chlorhexidine Acetate: Primarily used in the medical field, such as for skin and mucous membrane disinfection, wound disinfection, medical device sterilization, and as a bacteriostatic agent in pharmaceuticals. It exerts bactericidal and disinfecting effects through direct action on the human body, requiring extremely high standards for product safety and efficacy.- Food Grade Chlorhexidine Acetate: Mainly used in the food industry as a food additive for sterilization and preservation during food processing to extend shelf life and ensure microbial safety. It is generally not directly applied to the human body but enters indirectly through food additives, so its usage scope and limits in food are clearly defined.Regulatory Requirements for Chlorhexidine Acetate:- Pharmaceutical Grade: Subject to strict oversight by drug regulatory authorities, with a comprehensive regulatory system covering production licensing, product registration, and post-market adverse reaction monitoring to ensure drug quality, safety, and efficacy.- Food Grade: Regulated by food regulatory agencies, focusing on compliance, safety in food use, and its impact on food quality.Pharmaceutical-grade and food-grade chlorhexidine acetate differ significantly in quality standards, production processes, uses, and regulatory requirements. The appropriate grade should be selected based on specific needs, and the two should not be confused to avoid adverse consequences.Pharmaceutical Grade Chlorhexidine Acetate (Chlorhexidine Acetate) Disinfectant and Antiseptic Bulk Drug CP Edition Pharmacopoeia StandardCP Edition Quality Standards for Pharmaceutical Grade Chlorhexidine Acetate Bulk Drug1. Appearance and PropertiesPharmaceutical-grade chlorhexidine acetate should be a colorless or pale yellow transparent liquid, odorless, with a characteristic pungent odor. Its appearance should be clear and transparent, free of precipitates or suspended matter, meeting pharmacopoeial quality requirements.2. IdentificationThe pharmacopoeia stipulates that chlorhexidine acetate must meet the following identification criteria:- Ultraviolet Absorption Spectrum Identification: Chlorhexidine acetate should exhibit characteristic absorption peaks in the ultraviolet spectrum, aiding in confirming its chemical structure.- Reaction with Water: The aqueous solution of chlorhexidine acetate should demonstrate strong antibacterial activity, indicating its active ingredients comply with pharmacopoeial requirements.3. AssayThe effective content of chlorhexidine acetate must meet specified standards. Typically, its content is determined using high-performance liquid chromatography (HPLC). The pharmacopoeia requires the content of chlorhexidine acetate to be between 95.0% and 105.0% of the nominal value to ensure stable efficacy.4. Moisture ContentThe moisture content in pharmaceutical-grade chlorhexidine acetate must not exceed 5.0%. Excessive moisture may lead to degradation, affecting its stability and disinfecting efficacy.5. pH ValueThe solution of chlorhexidine acetate should have appropriate acidity, typically with a pH value between 4.5 and 6.5. pH values that are too low or too high may impact its efficacy and stability.6. Impurity TestingThe pharmacopoeia imposes strict regulations on impurity content in chlorhexidine acetate. Common impurities include degradation products of chlorhexidine and other harmful substances. Chlorhexidine acetate should not contain visible impurities, and its heavy metal and arsenic content should be below specified limits (e.g., arsenic not exceeding 2 ppm, heavy metals not exceeding 20 ppm).7. Microbial LimitsAs an antibacterial drug, chlorhexidine acetate must strictly control microbial contamination during production and storage to ensure it is free of pathogenic microorganisms. The pharmacopoeia requires pharmaceutical-grade chlorhexidine acetate to pass sterility testing, and the total microbial count must meet standard requirements. more>

$面谈

Category: Chemicals/Chemical Intermediates/Intermediate Compounds

Company: 陕西圣瑞医药科技有限公司

Product Description: Pharmaceutical Grade Nitrofurazone Disinfectant and Antiseptic Bulk API, Drug Approval Number, CDE Registration, Pharmacopoeia StandardPharmaceutical grade nitrofurazone is an important raw material for anti-infective drugs, widely used in pharmaceuticals, medical devices, and topical preparations. Its main function is antibacterial disinfection, particularly effective against wound infections, skin ulcers, and other conditions. According to the requirements of the Chinese Pharmacopoeia 2020 Edition (CP), the quality standards of nitrofurazone are strictly regulated to ensure its safety, efficacy, and stability in medications.1. Chemical Properties of Nitrofurazone- Chemical Name: Nitrofurazone.- Chemical Structure: A nitrofuran compound containing nitro and aldehyde functional groups.- Appearance and Properties:- Nitrofurazone is a yellow or orange-yellow crystalline powder.- It has a slight odor and certain chemical stability.- Solubility: Slightly soluble in water, easily soluble in dimethyl sulfoxide (DMSO) and ethanol.Pharmaceutical Grade Nitrofurazone Disinfectant and Antiseptic Bulk API, Drug Approval Number, CDE Registration, Pharmacopoeia Standard- Main Functions of Pharmaceutical Grade Nitrofurazone:- As an antibacterial agent, it is primarily used for the prevention and treatment of topical wound infections.- It exhibits bacteriostatic effects against various Gram-positive and Gram-negative bacteria.Quality Standards of Pharmaceutical Grade Nitrofurazone (CP Edition)According to the Chinese Pharmacopoeia 2020 Edition, nitrofurazone must meet the following quality control requirements:- Appearance: Yellow or orange-yellow crystalline powder, free from visible impurities upon visual inspection.- Identification: Confirmation of characteristic functional groups and chemical structure via ultraviolet absorption spectroscopy or infrared spectroscopy.- Assay: Nitrofurazone content must not be less than 98.0%.- Clarity and Color of Solution: Prepared aqueous solution should show no significant turbidity or abnormal color.- Melting Point Range: Should be between 240°C and 244°C.- Heavy Metal Limit: Must not exceed 20 ppm to ensure drug safety.- Impurity Testing: Related impurities must be controlled via thin-layer chromatography or high-performance liquid chromatography (HPLC) to ensure purity.- Loss on Drying: Total moisture and volatile substances must not exceed 0.5%.- Acidity or Alkalinity: The pH of the prepared solution must fall within the pharmacopoeia-specified range (typically 5.5-7.5).Medicinal Functions and Applications of NitrofurazoneAs a pharmaceutical raw material, the main uses of nitrofurazone include the following aspects:- Topical Antibacterial Agent:- Formulated into creams, ointments, or gauzes for local disinfection of wounds, burns, ulcers, and infectious skin diseases.- Applied in medical dressings to promote wound healing.- Surgical Infection Prevention:- Used in postoperative wound care to reduce the risk of bacterial infection.- Veterinary Applications:- In veterinary medicine, nitrofurazone is also commonly used as a topical anti-infective agent to treat animal wounds and skin ulcers. more>

$面谈

Category: Chemicals/Oxides/Other Oxides

Company: 陕西圣瑞医药科技有限公司

Product Description: Pharmaceutical Grade Sublimed Sulfur Medical Sublimed Sulfur Approved Drug Code Dermatological Antibacterial Active Pharmaceutical Ingredient GMP Certified 500g per BagSublimed Sulfur, commonly known as sulfur, is a chemical raw material widely used in pharmaceuticals, agriculture, and industry, known for its bactericidal and antibacterial effects. As a pharmaceutical ingredient, sublimed sulfur is often used in dermatological medications to treat skin conditions such as acne, eczema, and fungal infections. Its pharmaceutical-grade products must meet the quality standards of the "Chinese Pharmacopoeia 2020 Edition" (CP edition) to ensure safety and efficacy in medical applications.Pharmacopoeia Quality Standards for Pharmaceutical Grade Sublimed SulfurPharmaceutical grade sublimed sulfur is an important active pharmaceutical ingredient (API) in the medical field, with quality standards strictly adhering to the requirements of the "Chinese Pharmacopoeia" (CP). According to the pharmacopoeia, its core quality indicators are as follows:1. Purity requirement: Sulfur (S) content must not be less than 98.0%.2. Characteristics: Yellow crystalline powder with a slight odor, almost insoluble in water or ethanol.3. Identification methods:- Burns with a blue flame, accompanied by the irritating odor of sulfur dioxide;4. Inspection items:- Acidity: Must meet the requirement for light red indication;- Fineness: Not less than 85.0% of the powder passes through a No. 8 sieve;- Residue on ignition: Must not exceed 0.2%;- Arsenic salt: Content must not exceed 0.0012%.5. Assay: Determined by the oxygen flask combustion method, titrated with sodium hydroxide titration solution, where each 1 ml of titration solution is equivalent to 1.603 mg of sulfur.6. Storage: Must be kept sealed.Pharmaceutical Grade Sublimed Sulfur Medical Sublimed Sulfur Approved Drug Code Dermatological Antibacterial Active Pharmaceutical Ingredient GMP Certified 500g per BagI. Main Functions of Pharmaceutical Grade Sublimed Sulfur1. Antibacterial and BacteriostaticBy denaturing bacterial proteins and rendering them inactive, it inhibits bacterial reproduction and is effective against pathogenic bacteria such as Staphylococcus aureus and Escherichia coli.2. Insecticidal EffectIt can kill parasites such as scabies mites and pubic lice, making it suitable for treating parasitic infections like scabies and pubic lice infestations.3. Regulates Skin MetabolismReduces sebum secretion, improves abnormal follicular keratinization, and inhibits Propionibacterium acnes, thereby treating acne.4. Promotes Wound HealingReduces tissue edema through astringent effects and accelerates skin repair, making it suitable for superficial wounds or inflammatory skin lesions.Anti-inflammatory and Anti-itchDissolves the stratum corneum and constricts local blood vessels, alleviating itching symptoms. Commonly used for skin conditions such as seborrheic dermatitis and eczema. more>

$面谈

Category: Chemicals/Pharmaceutical Raw Materials/Chemical APIs

Company: 陕西圣瑞医药科技有限公司

Product Description: Pharmaceutical Grade Nitrofurazone Medical Grade Nitrofurazone National Drug Standard Code Active Pharmaceutical Ingredient Pharmacopoeia Standard Purity Above 99%Medical Uses of Pharmaceutical Grade NitrofurazoneNitrofurazone has broad-spectrum antibacterial effects, primarily by inhibiting bacterial protein synthesis and other intracellular physiological processes to kill or suppress bacterial growth. It is widely used in clinical settings, with main applications including:1. Treatment of Intestinal Infections: Nitrofurazone effectively inhibits various pathogenic bacteria and is commonly used to treat gastrointestinal infections caused by bacteria, especially acute diarrhea and dysentery caused by Salmonella, Shigella, and other bacteria. Its antibacterial properties make it one of the commonly used drugs in the treatment of intestinal infections.2. Treatment of Urinary System Infections: Nitrofurazone has a significant inhibitory effect on common urinary system pathogens such as Escherichia coli and Proteus, so it is often used to treat urinary tract infections (such as cystitis, urethritis) and to prevent infections after urinary tract surgery.3. Antibacterial and Antiviral Effects: Nitrofurazone has certain antiviral properties, capable of inhibiting the replication of some viruses, particularly showing strong inhibitory effects against certain enteroviruses. Therefore, it can also be used as an adjunct treatment for some viral diarrheas in clinical practice.4. Prevention of Postoperative Infections: After certain surgical procedures, nitrofurazone is often used to prevent infections, especially in high-risk surgeries such as intestinal and urinary system operations, where it effectively reduces the occurrence of bacterial infections.5. Topical Application: In addition to oral formulations, nitrofurazone can also be used as a topical medication to treat superficial skin infections. For example, certain local skin infections such as bacterial infections after burns or trauma can also be treated with topical nitrofurazone.Pharmaceutical Grade Nitrofurazone Medical Grade Nitrofurazone National Drug Standard Code Active Pharmaceutical Ingredient Pharmacopoeia Standard Purity Above 99%Pharmaceutical grade nitrofurazone is an important raw material for anti-infective drugs, widely used in pharmaceuticals, medical devices, and topical preparations. Its main function is antibacterial disinfection, particularly effective against wound infections and skin ulcers. According to the relevant requirements of the "Chinese Pharmacopoeia 2020 Edition" (CP edition), the quality standards of nitrofurazone are strictly regulated to ensure its safety, efficacy, and stability in medications.1. Chemical Properties of Nitrofurazone- Chemical Name: Nitrofurazone.- Chemical Structure: A nitrofuran compound containing nitro and aldehyde functional groups.- Appearance and Properties:- Nitrofurazone is a yellow or orange-yellow crystalline powder.- It has a slight odor and certain chemical stability.- Solubility: Slightly soluble in water, easily soluble in dimethyl sulfoxide (DMSO) and ethanol.- Main Functions:- As an antibacterial drug, it is mainly used to prevent and treat topical wound infections.- It has bacteriostatic effects against various Gram-positive and Gram-negative bacteria. more>

$面谈

Category: Chemicals/Chemical Intermediates/Intermediate Compounds

Company: 陕西圣瑞医药科技有限公司

Product Description: Pharmaceutical Grade Borneol Medical Grade Natural/Synthetic Borneol with Full National Drug Approval Number, Active Pharmaceutical Ingredient (API), CDE Filing QualificationsPharmaceutical grade borneol (synthetic borneol) has clear quality standards in the pharmacopoeia, and it possesses multiple pharmacological effects and uses. Here are some key points:Pharmacopoeia Quality Standards for Medicinal BorneolAccording to the standards of the Chinese Pharmacopoeia, pharmaceutical grade borneol (synthetic borneol) generally meets the following quality requirements:1. Appearance: White or off-white crystals or granules.2. Assay: The main component should be borneol, and its content must generally meet standard requirements.3. Moisture: Moisture content generally should not exceed 2%.4. Solubility: Good solubility in solvents such as alcohol.5. Heavy Metals: Must not exceed specified limits.6. Impurities: Must not contain excessive impurities and should comply with pharmacopoeia-specified limits.Pharmaceutical Grade Borneol Medical Grade Natural/Synthetic Borneol with Full National Drug Approval Number, Active Pharmaceutical Ingredient (API), CDE Filing QualificationsEffects and Uses of Medicinal Borneol:1. Pharmacological Effects:- Antibacterial Effect: Borneol has the ability to inhibit bacterial growth, particularly showing inhibitory effects against some common pathogenic bacteria.- Analgesic Effect: Borneol has certain analgesic properties and can be used to relieve mild pain.- Antipyretic Effect: It is also used in traditional Chinese medicine as a heat-clearing and detoxifying agent.- Anti-allergic Effect: Some studies suggest that borneol may have anti-allergic effects, helping to alleviate certain allergic symptoms.2. Main Uses of Medicinal Borneol:- Topical Medications: Used in some external applications to relieve skin itching, pain, burns, scalds, etc.- Respiratory Diseases: Often used in medications for treating upper respiratory infections (such as cooling oils, essential balms, etc.).- Central Nervous System: Commonly used in sedative and calming medications.- Traditional Chinese Medicine Applications: Used to treat symptoms such as headaches, nasal congestion, and coughs.The above content is an overview of pharmacopoeia standards and its main uses. For more detailed information or specific standards, please refer to the latest edition of the Chinese Pharmacopoeia. more>

$12

Category: Chemicals/Inorganic Salts/Other Inorganic Salts

Company: 陕西圣瑞医药科技有限公司

Product Description: Pharmaceutical Grade Potassium Citrate White Crystal Powder Medical Grade Potassium Citrate 500g per Bottle National Medicine Permit Number Active Pharmaceutical IngredientAs a commonly used clinical medication, pharmaceutical grade potassium citrate demonstrates significant efficacy in the treatment and prevention of various diseases. Its mechanism of action involves multiple physiological processes, which are detailed below.1. Supplementing Potassium Ions and Correcting HypokalemiaPotassium ions are important cations within human cells, playing a key role in maintaining normal cellular metabolism, neuromuscular excitability, and normal function. When the body loses excessive potassium due to various reasons (such as inadequate intake, vomiting, diarrhea, long-term use of potassium-wasting diuretics) or insufficient potassium intake, hypokalemia occurs. Hypokalemia can cause a range of symptoms, including muscle weakness and arrhythmias.After ingestion, pharmaceutical grade potassium citrate dissociates into potassium ions in the gastrointestinal tract. These potassium ions enter the bloodstream through active transport and passive diffusion across the intestinal mucosal cells. They are then transported into the cells, replenishing the deficient intracellular potassium, restoring the balance of potassium concentrations inside and outside the cells, thereby correcting hypokalemia and restoring normal neuromuscular excitability and normal rhythm.2. Regulating Acid-Base Balance and Improving Renal Tubular AcidosisRenal tubular acidosis results from impaired renal tubule function, reducing the kidney's ability to regulate acid-base balance, leading to accumulation of acidic substances or loss of alkaline substances in the body, resulting in acidosis. In patients with type I distal renal tubular acidosis accompanied by hypokalemia, pharmaceutical grade potassium citrate plays a significant therapeutic role.After metabolism in the body, the citrate ions from potassium citrate participate in the tricarboxylic acid cycle, ultimately being oxidized to carbon dioxide and water, and generating bicarbonate ions (HCO₃⁻). HCO₃⁻ is an important alkaline substance in the body that can neutralize excess acids, increase blood pH, and correct acidosis. Simultaneously, potassium supplementation helps improve the function of renal tubular cells, further promoting the restoration of acid-base balance.3. Altering Urine Composition and Preventing Urinary System StonesThe formation of urinary system stones is closely related to the concentration and solubility of various components in urine. Pharmaceutical grade potassium citrate prevents urinary stones primarily through the following mechanisms:Inhibiting Calcium Oxalate Stone Formation: In urine, calcium oxalate is one of the main components of kidney stones. The citrate ions from potassium citrate can bind with calcium ions to form soluble calcium citrate complexes. This reduces the concentration of free calcium ions in urine, decreasing the chance of calcium ions combining with oxalate ions to form calcium oxalate crystals, thereby inhibiting stone formation. Additionally, calcium citrate complexes have high solubility and are less likely to precipitate, helping prevent stone growth.Dissolving Uric Acid Stones: Uric acid has low solubility in acidic urine and is prone to crystallize into stones. After ingestion, pharmaceutical grade potassium citrate increases urine pH, making it alkaline. In an alkaline environment, the solubility of uric acid significantly increases, and existing uric acid stones gradually dissolve, thus preventing and treating uric acid stones.4. Influencing Electrophysiology and Alleviating ArrhythmiasIn cases of arrhythmias caused by digitalis toxicity, pharmaceutical grade potassium citrate can also provide therapeutic benefits. Potassium ions significantly influence the electrophysiological properties of myocardial cells. During hypokalemia, myocardial cell excitability increases, automaticity enhances, and arrhythmias are more likely to occur. After supplementation with pharmaceutical grade potassium citrate, potassium ions enter myocardial cells, restoring the resting membrane potential, reducing excitability and automaticity, and improving conduction, thereby correcting arrhythmias caused by hypokalemia or digitalis toxicity and restoring normal rhythm.Pharmaceutical Grade Potassium Citrate White Crystal Powder Medical Grade Potassium Citrate 500g per Bottle National Medicine Permit Number Active Pharmaceutical IngredientFunctions of Potassium CitratePotassium Citrate Uses, Effects, Dosage, and AdministrationEffects and Benefits of Potassium CitrateDifference Between Potassium Citrate and Potassium ChlorideDifference Between Potassium Citrate and Potassium Sodium Hydrogen CitrateIs Potassium Citrate a Traditional Chinese Medicine or Western Medicine?Where to Buy Potassium CitratePharmaceutical Grade Potassium CitrateUses and Benefits of Potassium CitrateFunctions of Potassium CitratePotassium Citrate Uses, Effects, Dosage, and AdministrationUses and Applications of Potassium Citrate SolutionDifference Between Potassium Citrate and Potassium ChlorideWhat Category of Drug is Potassium Citrate?Which is Better: Potassium Citrate or Potassium Chloride?What is Another Name for Potassium Citrate Granules?Efficacy and Functions of Potassium CitrateDifference Between Potassium Citrate and Potassium Sodium Hydrogen CitrateUses and Applications of Potassium Citrate SolutionDifference Between Potassium Citrate and Citrate MixtureDifference Between Potassium Citrate and Potassium ChlorideEfficacy of Potassium Citrate TabletsComposition of Potassium Citrate more>

$面谈

Category: Chemicals/Chemical Intermediates/Intermediate Compounds

Company: 陕西圣瑞医药科技有限公司

Product Description: Pharmaceutical Grade Artificial Bezoar National Drug Approval Number Medical Grade Artificial Bezoar Active Pharmaceutical Ingredient Grade CDE Registration Number AArtificial bezoar is an important medicinal raw material widely used in traditional Chinese medicine and modern pharmaceutical preparations. As a substitute for natural bezoar, artificial bezoar demonstrates excellent efficacy and safety, while also offering advantages in cost and stability. The "Chinese Pharmacopoeia 2020 Edition" (CP Edition) sets strict quality standards for pharmaceutical-grade artificial bezoar to ensure its safe, effective, and compliant application in the pharmaceutical industry.1. Properties of Artificial BezoarArtificial bezoar is a yellow-brown or orange-yellow powder with the characteristic odor of natural bezoar and exhibits certain solubility in both water and ethanol. It is a complex chemical mixture primarily composed of bilirubin, bile acids, cholesterol, and trace elements, possessing anti-inflammatory, antioxidant, and antipyretic effects.2. Quality StandardsAccording to the "Chinese Pharmacopoeia 2020 Edition," artificial bezoar must meet the following quality requirements:- Identification: The components of artificial bezoar can be identified through microscopic observation or chemical analysis methods, such as ultraviolet-visible spectrophotometry to analyze its characteristic absorption peaks.- Content Determination:- Bilirubin content must be within the range of 35.0%-41.0%, which is a key indicator for judging the quality of artificial bezoar.- Bile acid content must reach 10.0%-15.0%.- Impurity Limits:- Heavy metal limits should be less than 10 ppm to ensure safety.- Arsenic salt content must not exceed 2 ppm to prevent potential toxicity.- Microbial Limits:- As a medicinal raw material, artificial bezoar requires strict control of microbial contamination to ensure that total bacterial count, molds, and yeasts meet pharmacopoeia requirements.- Loss on Drying: Should not exceed 5.0% to ensure product stability.3. UsesArtificial bezoar is primarily used in various pharmaceutical preparations to exert effects such as clearing heat and detoxifying, calming the mind, anticonvulsant, and anti-inflammatory. Common dosage forms include capsules, tablets, and injections, such as Bezoar Detoxification Tablets and Bezoar Heart-Clearing Pills.Pharmaceutical Grade Artificial Bezoar National Drug Approval Number Medical Grade Artificial Bezoar Active Pharmaceutical Ingredient Grade CDE Registration Number AArtificial Bezoar Price ListEfficacy and Functions of Traditional Chinese Medicine Artificial BezoarDifference Between Artificial Bezoar and Natural BezoarAre Artificial Bezoar and Natural Bezoar Equally Effective?Alternative Names for Artificial BezoarTraditional Chinese Medicine Artificial BezoarIs Pharmaceutical Grade Higher Than Medical Grade?Pictures Showing Differences Between Natural Bezoar and Artificial BezoarWhat Is Artificial Bezoar Made Of?What Is the Difference Between Bezoar and Artificial Bezoar? more>