Introduction to the characteristics and advantages of MAOS as a chromogenic substrate
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Company: Hubei new DE sheng material science and technology co., LTD.
Product Description: MAOS (CASNo.: 82692-97-5), also known as N-ethyl-N - (2-hydroxy-3-sulfopropyl) -3,5-dimethylaniline sodium salt monohydrate, is a very important member of the new Trinder's reagent family. It's not as commonly used as TOOS, but
But it also has an absolutely irreplaceable role. Like other new color reagents, they have high water solubility and much higher sensitivity than traditional color reagents commonly used in some laboratories, making them widely used in clinical testing and biochemical reagent kits.
MAOS has a high absorption wavelength
The biggest characteristic of MAOS is that the maximum absorption wavelength of its oxidized product far exceeds that of ordinary color reagents. Even in the new Trinder's reagent, its product has a relatively high UV absorption wavelength of 630nm. The maximum absorption wavelength of many color reagent products is in the visible light region. If it is used to detect human blood or other body fluids, due to the complexity of the components in the sample to be tested, the sample itself contains a small amount of components with absorption wavelengths in the visible light region or similar to the absorption wavelength of the color product, which will result in higher detection results. If using MAOS, the maximum absorption wavelength of the product is in the ultraviolet region and relatively high, it will greatly reduce interference. Therefore, for some biochemical testing items that require highly accurate values, it is recommended to use MAOS as the chromogenic substrate.
PH value of MAOS
Secondly, the color reaction of MAOS chromogenic substrate has a wide adaptability range to the pH of the reaction system, greatly improving its adaptability
Sex. Some color reagents often react under slightly acidic conditions, but enzyme involvement is usually required in biochemical testing. We know that enzyme catalysis is sensitive to the pH of the reaction environment, and it may even become inactive if it does not match the color reagents. Its use is greatly limited, while MAOS reagents do not have this problem.
Molar absorbance of MAOS
Another point is that the molar absorption intensity of MAOS color reaction is relatively high, so its sensitivity is also relatively high. Attention Required
However, when the detection time is too long, MAOS may fade, so MAOS detection needs to be completed in a timely manner and cannot be interrupted. In addition, MAOS is also relatively safe, unlike DAB and other biphenyl chromogenic reagents, which are relatively inexpensive but have
Has certain carcinogenicity or mutagenicity.
Storage of MAOS
MAOS is sensitive to light and humidity, so it has high storage requirements. It is necessary to use containers that are well shaded and sealed, with a temperature of 0-5 ℃. It is best to store them in cold storage, while also paying attention to avoiding light and moisture to ensure higher and more accurate testing quality.
Desheng Technology has always been committed to the research and development, production, and sales of chromogenic substrates, especially TOOS, MAOS, ADPS, etc., which have a good reputation both domestically and internationally. We have good cooperative relationships with many biochemical reagent kit manufacturers. Let's work together to add bricks and tiles to the field of domestic diagnostic reagents!
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