
Title: PANTOPRAZOLE SODIUM
CAS Registry Number: 138786-67-1
Trademarks: Eupantol (Altana); Pantecta (Pfizer); Pantozol (Altana); Pantopan (Pharmacia); Pantorc (Altana); Peptazol (Recordati); Protium (Altana); Protonix (Wyeth); Somac (Pfizer)
Molecular Formula: C16H14F2N3NaO4S
Molecular Weight: 405.35
Percent Composition: C 47.41%, H 3.48%, F 9.37%, N 10.37%, Na 5.67%, O 15.79%, S 7.91%
Properties: Prepd as the sesquihydrate. White to off-white crystalline powder, dec >130°. uv max (methanol): 289 (e 1.64 ´ 104). Freely sol in water; very slightly sol in phosphate buffer (pH 7.4). Practically insol in n-hexane.
Absorption maximum: uv max (methanol): 289 (e 1.64 ´ 104)
Purity:≥99%
Therap-Cat: Antiulcerative; in treatment of Zollinger-Ellison syndrome.
Keywords: Antiulcerative; Gastric Proton Pump Inhibitor.