Dissolution Tester

Drug Dissolution Tester is a specialized pharmaceutical testing instrument used to detect the dissolution rate of solid preparations (such as tablets, capsules, etc.). It simulates the human gastrointestinal digestive movement process and, when used in conjunction with an ultraviolet spectrophotometer, can measure the dissolution rate of pharmaceutical preparations.

This is an in vitro testing method for controlling the quality of pharmaceutical preparations and has been widely applied in drug research, production, and inspection. The improved dissolution tester uses imported motors, ensuring accurate rotational speed and stable operation. The instrument consists of components such as the cabinet, control system, water bath system, transmission system, and built-in sensors. A precision control system, composed of a single-chip microcomputer, centrally controls all components. The instrument features a high degree of automation, precise control, minimal error, low noise, and ease of operation. The dissolution tester cabinet is composed of the machine head, electrical box, front control panel, water bath tank, and other parts.

Drug Dissolution Tester main technical parameters are as follows:

I. Paddle and Basket Shafts (collectively referred to as rotating shafts)

l 1. Dimensions comply with the Chinese Pharmacopoeia standards

l 2. Paddle shaft oscillation amplitude: ≤±0.5mm

l 3. Basket oscillation amplitude: ≤±1mm

l 4. Rotating shaft and dissolution vessel coaxiality: ≤2mm

II. Rotating Shaft Speed Control

l 1. Speed adjustment range: 25–200 rpm

l 2. Speed resolution: 1 rpm

l 3. Speed stability error: ≤±4%

III. Water Bath Temperature Control

l 1. Temperature adjustment range: 5.0 (room temperature) – 45.0°C

l 2. Temperature resolution: 0.1°C

l 3. Temperature control error: ≤±0.3°C

IV. Test Time Control

l 1. Cumulative timing: Up to 99 hours and 59 minutes, forward timing

l 2. Number of sampling cycles: Up to 9 different sampling cycles

l 3. Sampling cycle time: Up to 9 hours and 59 minutes per cycle, countdown

l 4. Timed on/off time: Up to 99 hours and 59 minutes, countdown

V. Operating Noise: <60dB

VI. Continuous Operating Time: 48 hours

VII. Safety Performance: Complies with the national professional standard JB/T20076-2005, with self-check and automatic protection functions

VIII. Power Supply: AC200V±10%, 50Hz, 1300W

IX. Environmental Conditions: Ambient temperature 5–35°C, relative humidity ≤80%