n-Butyric acid

Core Application Areas

1. Food Industry: Flavoring and Preservation

Spice Additives: Utilizing its natural buttery flavor, it is used to formulate essences for cream, cheese, ice cream, etc. (FEMA No. 2221). China's GB2760 permits its use with a maximum usage level of 0.15g/kg (for cold drinks).

Preservatives: Inhibits the growth of molds and bacteria by lowering the pH of food; used in pickles and silage (combined with propionic acid to enhance efficacy).

2. Chemical Industry: Synthetic Intermediates

Ester Preparation: Esterification with methanol, ethanol, glycerol, etc., to generate butyrate esters, such as: Ethyl butyrate (fruit flavoring, used in beverages and candies);

Glycerol butyrate (feed additive, improving animal intestinal health);

Butyl cellulose (plasticizer for coatings and adhesives).

Polymer Monomers: Polymerized with diols to produce polyesters (used in biodegradable materials), or used as a comonomer to synthesize acrylate resins (improving water resistance).

3. Pharmaceuticals and Health

Butyrate Drugs: Sodium butyrate (n-butyrate) acts as a histone deacetylase inhibitor, used in the treatment of ulcerative colitis (regulating gut flora, inhibiting inflammation), and also in cancer research (inducing cancer cell apoptosis).

Skin Care: Low concentration (0.5%-2%) n-butyric acid is used in stratum corneum regulation products to promote skin metabolism (similar to the effects of fruit acids).

4. Agriculture and Animal Husbandry

Feed Additives: Sodium butyrate (or glycerol butyrate) serves as an intestinal prebiotic, promoting the development of intestinal mucosa in piglets and broilers, and improving feed conversion rates (addition amount 0.1%-0.3%);

Plant Growth Regulators: Low concentration n-butyric acid can promote crop rooting and fruit maturation.

5. Other Applications

Textile Industry: Used for wool degreasing and as a dyeing auxiliary;

Organic Synthesis: Used as a raw material for the preparation of compounds such as butyronitrile and butylamine;

Environmental Protection: Used for treating nitrogen-containing wastewater, reducing ammonia nitrogen concentration through microbial conversion.